Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | MITF | O75030 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.38 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tert-Butyl Formate SCHEMBL28011981 | 1.00 | FDPS (0.41) | FDPSTDP1LMNAMEN1TP53 | |
| Tert-Butyl Formate SCHEMBL28876453 | 0.85 | FDPS (0.43) | FDPSTDP1LMNAMEN1TP53 | |
| Tert-Butyl Formate SCHEMBL27841275 | 0.85 | FDPS (0.43) | FDPSTDP1LMNAMEN1TP53 | |
| Tert-Butyl Formate SCHEMBL27711380 | 0.85 | FDPS (0.43) | FDPSTDP1LMNAMEN1TP53 | |
| Tert-Butyl Formate SCHEMBL27723860 | 0.85 | FDPS (0.43) | FDPSTDP1LMNAMEN1TP53 | |
| SCHEMBL8116639 | 0.84 | FDPS (0.50) | FDPSLMNAMEN1TP53KMT2A | |
| SCHEMBL5058596 | 0.84 | FDPS (0.50) | FDPSLMNAMEN1TP53KMT2A | |
| SCHEMBL156790 | 0.84 | FDPS (0.50) | FDPSLMNAMEN1TP53KMT2A | |
| SCHEMBL31318443 | 0.84 | FDPS (0.50) | FDPSLMNAMEN1TP53KMT2A | |
| Tert-Butyl Formate SCHEMBL27746517 | 0.83 | TDP1 (0.42) | FDPSTDP1LMNAMEN1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104583211-A | Compounds and methods for antiviral therapy | GILEAD SCIENCES INC | 2015-04-29 | — | — | CN | disclosed |