SCHEMBL28011986

SCHEMBL28011986

CCCCCCCCCCc1cc(-c2ccncc2)ccn1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2D6 P10635 2/20 0.49
CYP3A4 P08684 2/20 0.49
KCNH2 Q12809 1/20 0.44
SREBF2 Q12772 8/20 0.40
GSK3B P49841 2/20 0.38
PSEN1 P49768 1/20 0.38
PSEN2 P49810 1/20 0.38
APH1B Q8WW43 1/20 0.38
NCSTN Q92542 1/20 0.38
APH1A Q96BI3 1/20 0.38
PSENEN Q9NZ42 1/20 0.38
KDM4E B2RXH2 3/20 0.38
LMNA P02545 3/20 0.38
TSHR P16473 2/20 0.38
MAPT P10636 3/20 0.38
L3MBTL1 Q9Y468 3/20 0.38
ALDH1A1 P00352 2/20 0.38
ATM Q13315 2/20 0.38
NPC1 O15118 1/20 0.38
RAB9A P51151 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28012363 1.00 CYP2D6 (0.49) CYP2D6CYP3A4KCNH2SREBF2GSK3B
SCHEMBL27913958 1.00 CYP2D6 (0.49) CYP2D6CYP3A4KCNH2SREBF2GSK3B
SCHEMBL28011947 1.00 CYP2D6 (0.49) CYP2D6CYP3A4KCNH2SREBF2GSK3B
SCHEMBL28078531 1.00 CYP2D6 (0.49) CYP2D6CYP3A4KCNH2SREBF2GSK3B
SCHEMBL31345539 0.89 SREBF2 (0.51) KCNH2SREBF2
SCHEMBL27692764 0.89 SREBF2 (0.51) KCNH2SREBF2
SCHEMBL28292679 0.87 CYP2D6 (0.46) CYP2D6CYP3A4SREBF2GSK3BPSEN1
SCHEMBL25500863 0.87 SREBF2 (0.52) KCNH2SREBF2
SCHEMBL28684192 0.86 SREBF2 (0.50) CYP2D6CYP3A4SREBF2PSEN1PSEN2
Bromide SCHEMBL28704512 0.84 MAPT (0.50) CYP2D6CYP3A4SREBF2PSEN1PSEN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104610132-A Viologen compound, preparation method and application thereof BEIJING INST FASHION TECH 2015-05-13 CN disclosed