Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | SREBF2 | Q12772 | 9/20 | 0.41 |
| ▸ | GSK3B | P49841 | 1/20 | 0.40 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.39 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.39 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.39 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.39 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.39 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.39 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.37 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.37 |
| ▸ | RELA | Q04206 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28078531 | 0.87 | CYP2D6 (0.49) | CYP2D6CYP3A4SREBF2GSK3BPSEN1 | |
| SCHEMBL27913958 | 0.87 | CYP2D6 (0.49) | CYP2D6CYP3A4SREBF2GSK3BPSEN1 | |
| SCHEMBL28011986 | 0.87 | CYP2D6 (0.49) | CYP2D6CYP3A4SREBF2GSK3BPSEN1 | |
| SCHEMBL28012363 | 0.87 | CYP2D6 (0.49) | CYP2D6CYP3A4SREBF2GSK3BPSEN1 | |
| SCHEMBL28011947 | 0.87 | CYP2D6 (0.49) | CYP2D6CYP3A4SREBF2GSK3BPSEN1 | |
| SCHEMBL28684192 | 0.83 | SREBF2 (0.50) | CYP2D6CYP3A4SREBF2PSEN1PSEN2 | |
| Bromide SCHEMBL28704512 | 0.82 | MAPT (0.50) | CYP2D6CYP3A4SREBF2PSEN1PSEN2 | |
| SCHEMBL25500863 | 0.81 | SREBF2 (0.52) | SREBF2 | |
| SCHEMBL31345539 | 0.79 | SREBF2 (0.51) | SREBF2 | |
| SCHEMBL27692764 | 0.79 | SREBF2 (0.51) | SREBF2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109690395-A | Color offset in electrochromic device is alleviated | 金泰克斯公司 | 2019-04-26 | — | — | CN | claimed |