Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 3/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | FYN | P06241 | 1/20 | 0.35 |
| ▸ | APEX1 | P27695 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7048035 | 0.75 | — | — | |
| SCHEMBL9074096 | 0.74 | TYR (0.50) | ESR1ESR2KDM4EALDH1A1CYP3A4 | |
| SCHEMBL2040206 | 0.73 | GABRA1 (0.43) | ESR1ESR2ALDH1A1HPGDALOX15 | |
| SCHEMBL11495521 | 0.71 | TYR (0.56) | ESR1KDM4EALDH1A1CYP3A4MAPT | |
| SCHEMBL816624 | 0.71 | TYR (0.56) | ESR1KDM4EALDH1A1CYP3A4MAPT | |
| SCHEMBL27880027 | 0.71 | TYR (0.56) | ESR1KDM4EALDH1A1CYP3A4MAPT | |
| SCHEMBL27548329 | 0.71 | PTPN1 (0.40) | KDM4EALDH1A1CYP1A2CYP3A4MAPT | |
| SCHEMBL1719554 | 0.70 | NR5A2 (0.48) | ESR1ESR2ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL9847378 | 0.70 | GRIK1 (0.41) | MAPTGAAMAPK1XBP1ATM | |
| SCHEMBL1487540 | 0.70 | BLM (0.51) | ESR1ESR2KDM4EALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101650451-B | Light conducting plate | SUMITOMO CHEMICAL CO | 2015-04-29 | — | — | CN | disclosed |