⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL560454 | 0.74 | ALDH1A1 (0.59) | — | |
| SCHEMBL331716 | 0.71 | — | — | |
| SCHEMBL2801836 | 0.69 | — | — | |
| SCHEMBL9770740 | 0.69 | — | — | |
| SCHEMBL374821 | 0.69 | — | — | |
| SCHEMBL24803058 | 0.69 | — | — | |
| SCHEMBL437835 | 0.69 | ALDH1A1 (0.53) | — | |
| SCHEMBL284897 | 0.69 | — | — | |
| Sulfamic Acid Isopropyl Ester SCHEMBL284898 | 0.69 | — | — | |
| SCHEMBL18649881 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200017490-A1 | Novel Mesoionic Insecticidal Compound | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 2020-01-16 | — | — | US | disclosed |
| EP-3287457-B1 | MESOIONIC COMPOUND | NIPPON KAYAKU KK (JP) | 2019-09-18 | — | — | EP | disclosed |
| EP-3521287-A1 | NOVEL MESOIONIC INSECTICIDAL COMPOUND | Nippon Kayaku Kabushiki Kaisha (JP) | 2019-08-07 | — | — | EP | disclosed |
| US-20180310564-A1 | Mesoionic Compound | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 2018-11-01 | — | — | US | disclosed |
| EP-3287457-A1 | MESOIONIC COMPOUND | Nippon Kayaku Kabushiki Kaisha (JP) | 2018-02-28 | — | — | EP | disclosed |
| EP-2244710-A1 | A METHOD OF ADMINISTERING A PDE3 INHIBITOR VIA TITRATION FOR THE TREATMENT OF PERIPHERAL ARTERIAL DISEASE | Indigo Pharmaceuticals (US) | 2010-11-03 | — | — | EP | disclosed |
| WO-2010099388-A1 | COMBINATIONAL USE OF A PDE3 INHIBITOR AND OTHER AGENTS | INDIGO PHARMACEUTICALS (US) | 2010-09-02 | — | — | WO | disclosed |
| US-7612197-B2 | Reacting a nucleophil with OH group with an electrophil to form an adduct, reacting adduct with a reagent selected from oxidizing, sulfurizing or selenizing agents to produce hydroxy protected oligonucleotide, heating to deprotect hydroxy protecting group such as 2-(2-pyridyl)aminoethoxycarbonyl | The United States of America as repesented by the Secretary of the Department of Health and Human Services (US) | 2009-11-03 | — | — | US | disclosed |
| WO-2009097406-A1 | A METHOD OF ADMINISTERING A PDE3 INHIBITOR VIA TITRATION FOR THE TREATMENT OF PERIPHERAL ARTERIAL DISEASE | INDIGO PHARMACEUTICALS (US) | 2009-08-06 | — | — | WO | disclosed |
| US-20080200336-A1 | HERBICIDAL COMPOSITION | SYNEGENTA CROP PROTECTION, INC. (US) | 2008-08-21 | — | — | US | disclosed |
| WO-2001017353-A1 | HERBICIDAL COMPOSITION | SYNGENTA PARTICIPATIONS AG (CH) | 2001-03-15 | — | — | WO | disclosed |
| EP-0482208-B1 | PYRIDAZINONE DERIVATIVE | NISSAN CHEMICAL IND LTD (JP) | 2000-07-19 | — | — | EP | disclosed |
| US-5318968-A | Antithrombotic agents; cardiotonic agents; vasodilators | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1994-06-07 | — | — | US | disclosed |
| US-5314883-A | Vasodilation, anticoagulants | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1994-05-24 | — | — | US | disclosed |
| US-5231101-A | Antihistamines | SS PHARMACEUTICAL CO., LTD. (JP) | 1993-07-27 | — | — | US | disclosed |
| US-5202323-A | Antithrombotic, inotropic, vasodilator, antiallergen | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1993-04-13 | — | — | US | disclosed |
| EP-0495484-A1 | Novel benzo [5,6] cyclohepta [1,2-b] pyridine derivatives and antiallergic agents comprising same | SS PHARMACEUTICAL CO., LTD. (JP) | 1992-07-22 | — | — | EP | disclosed |
| EP-0482208-A1 | PYRIDAZINONE DERIVATIVE | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1992-04-29 | — | — | EP | disclosed |
| US-4859229-A | HERBICIDES | HOFFMANN-LA ROCHE INC. (US) | 1989-08-22 | — | — | US | disclosed |
| EP-0255047-A1 | 3-Aryl uraciles and their use as herbicides | CIBA-GEIGY AG (CH) | 1988-02-03 | — | — | EP | disclosed |