Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACMSD | Q8TDX5 | 2/20 | 0.45 |
| ▸ | CAMKK2 | Q96RR4 | 6/20 | 0.42 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | FASN | P49327 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMO | O15229 | 2/20 | 0.39 |
| ▸ | CAMKK1 | Q8N5S9 | 3/20 | 0.39 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15543706 | 0.85 | FASN (0.54) | ACMSDCAMKK2MAPTFASNKDM4E | |
| SCHEMBL21095458 | 0.84 | MAPT (0.41) | ACMSDCAMKK2PTGDR2MAPTFASN | |
| SCHEMBL3810008 | 0.83 | ACMSD (0.50) | ACMSDCAMKK2PTGDR2MAPTKDM4E | |
| SCHEMBL15544569 | 0.83 | FASN (0.54) | CAMKK2FASN | |
| SCHEMBL12488234 | 0.83 | FASN (0.39) | CAMKK2MAPTFASNKDM4E | |
| SCHEMBL28974042 | 0.81 | FASN (0.38) | CAMKK2MAPTFASN | |
| SCHEMBL12488784 | 0.80 | MAPT (0.38) | ACMSDCAMKK2PTGDR2MAPTFASN | |
| SCHEMBL12488182 | 0.79 | MAPT (0.37) | ACMSDCAMKK2PTGDR2MAPTFASN | |
| SCHEMBL18304696 | 0.78 | PTGDR2 (0.57) | ACMSDCAMKK2PTGDR2CAMKK1 | |
| SCHEMBL31212649 | 0.78 | FASN (0.45) | FASNKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104582703-A | H4 receptor inhibitors for treating tinnitus | SENSORION | 2015-04-29 | — | — | CN | disclosed |