Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 13/20 | 0.64 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.43 |
| ▸ | TTR | P02766 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | LTA4H | P09960 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15538629 | 0.91 | BRD4 (0.61) | BRD4FFAR4PTGS2 | |
| SCHEMBL28012062 | 0.91 | BRD4 (0.64) | BRD4FFAR4PTGS2 | |
| SCHEMBL15538363 | 0.89 | BRD4 (0.59) | BRD4FFAR4PTGS2 | |
| SCHEMBL28012051 | 0.89 | BRD4 (0.65) | BRD4FFAR4PTGS2 | |
| SCHEMBL20135835 | 0.88 | BRD4 (0.58) | BRD4FFAR4 | |
| SCHEMBL15559351 | 0.88 | BRD4 (0.60) | BRD4FFAR4PTGS2 | |
| SCHEMBL15539387 | 0.87 | BRD4 (0.57) | BRD4FFAR4PTGS2 | |
| SCHEMBL15539499 | 0.87 | BRD4 (0.62) | BRD4FFAR4PTGS2 | |
| SCHEMBL15538774 | 0.87 | BRD4 (0.56) | BRD4FFAR4PTGS2 | |
| SCHEMBL15541113 | 0.86 | BRD4 (0.58) | BRD4FFAR4PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104884451-A | Pyridinone and pyridazinone derivatives | ABBVIE INC | 2015-09-02 | — | — | CN | disclosed |
| CN-104718201-A | Pyridinone and pyridazinone derivatives | ABBVIE INC | 2015-06-17 | — | — | CN | disclosed |