Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.90 |
| ▸ | ESR1 | P03372 | 3/20 | 0.50 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.50 |
| ▸ | PPARA | Q07869 | 6/20 | 0.44 |
| ▸ | PPARG | P37231 | 5/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.36 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.36 |
| ▸ | PSMB2 | P49721 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.35 |
| ▸ | ELANE | P08246 | 1/20 | 0.34 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Clinofibrate SCHEMBL20339978 | 0.95 | ADORA3 (1.00) | ADORA3ESR1ESR2PPARAPPARG | |
| Clinofibrate SCHEMBL3955329 | 0.95 | ADORA3 (1.00) | ADORA3ESR1ESR2PPARAPPARG | |
| Clinofibrate SCHEMBL31290 | 0.95 | ADORA3 (1.00) | ADORA3ESR1ESR2PPARAPPARG | |
| Clinofibrate SCHEMBL11223466 | 0.94 | ADORA3 (0.97) | ADORA3ESR1ESR2PPARAPPARG | |
| SCHEMBL12918479 | 0.91 | ADORA3 (0.92) | ADORA3ESR1ESR2PPARAPPARG | |
| SCHEMBL12918476 | 0.90 | ADORA3 (0.90) | ADORA3ESR1ESR2PPARAPPARG | |
| SCHEMBL12918474 | 0.89 | ADORA3 (0.88) | ADORA3PPARAPPARGMEN1KMT2A | |
| SCHEMBL15682176 | 0.88 | ADORA3 (0.69) | ADORA3ESR1ESR2PPARAPPARG | |
| SCHEMBL5141872 | 0.84 | ADORA3 (0.60) | ADORA3ESR1ESR2PPARAPPARG | |
| SCHEMBL5369095 | 0.84 | ADORA3 (0.60) | ADORA3ESR1ESR2PPARAPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104610051-A | Method for preparing clinofibrate impurities | BEIJING VENTUREPHARM BIOTECH CORP | 2015-05-13 | — | — | CN | disclosed |