Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | CTSC | P53634 | 1/20 | 0.32 |
| ▸ | KDM2B | Q8NHM5 | 2/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | DPP4 | P27487 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL337329 | 1.00 | HTR6 (0.36) | HTR6TDP1CTSCKDM2BALDH1A1 | |
| SCHEMBL1962915 | 1.00 | HTR6 (0.36) | HTR6TDP1CTSCKDM2BALDH1A1 | |
| SCHEMBL3337642 | 1.00 | HTR6 (0.36) | HTR6TDP1CTSCKDM2BALDH1A1 | |
| SCHEMBL9992744 | 1.00 | HTR6 (0.36) | HTR6TDP1CTSCKDM2BALDH1A1 | |
| SCHEMBL336904 | 1.00 | HTR6 (0.36) | HTR6TDP1CTSCKDM2BALDH1A1 | |
| SCHEMBL337871 | 0.95 | HTR6 (0.43) | HTR6TDP1DPP4 | |
| SCHEMBL24106650 | 0.81 | HTR6 (0.36) | HTR6CTSC | |
| SCHEMBL25270380 | 0.81 | HTR6 (0.36) | HTR6CTSC | |
| SCHEMBL24179707 | 0.81 | HTR6 (0.36) | HTR6CTSCALDH1A1DPP4 | |
| SCHEMBL8239226 | 0.81 | HTR6 (0.36) | HTR6CTSC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010091104-A1 | GLUCOSYLCERAMIDE SYNTHASE INHIBITORS | EXELIXIS, INC. (US) | 2010-08-12 | — | — | WO | disclosed |