Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.46 |
| ▸ | ADORA2A | P29274 | 5/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 5/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | IL4 | P05112 | 1/20 | 0.35 |
| ▸ | ATP4A | P20648 | 2/20 | 0.35 |
| ▸ | ATP4B | P51164 | 2/20 | 0.35 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.35 |
| ▸ | AR | P10275 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3452347 | 0.74 | KDM4E (0.70) | KDM4EALDH1A1RAB9AALOX5ADORA2A | |
| SCHEMBL17710271 | 0.71 | RAB9A (0.40) | KDM4EALDH1A1RAB9AALOX5ADORA2A | |
| SCHEMBL730687 | 0.71 | RAB9A (0.45) | KDM4EALDH1A1RAB9AALOX5ADORA2A | |
| SCHEMBL17200126 | 0.69 | HSP90AA1 (0.66) | KDM4EALDH1A1RAB9AADORA2AMEN1 | |
| SCHEMBL5511069 | 0.69 | KDM4E (0.64) | KDM4EALDH1A1RAB9AALOX5ADORA2A | |
| SCHEMBL29914245 | 0.68 | ADORA1 (0.68) | KDM4EALDH1A1RAB9AALOX5ADORA2A | |
| SCHEMBL2326019 | 0.68 | ADORA1 (0.68) | KDM4EALDH1A1RAB9AALOX5ADORA2A | |
| SCHEMBL1644353 | 0.67 | HSP90AA1 (0.68) | KDM4EALDH1A1RAB9AALOX5ADORA2A | |
| SCHEMBL13127057 | 0.67 | KDM4E (0.60) | KDM4EALDH1A1RAB9AALOX5ADORA2A | |
| SCHEMBL3451384 | 0.67 | KDM4E (0.60) | KDM4EALDH1A1RAB9AALOX5ADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104725322-A | 2-amido pyrimidine compound and preparation method thereof | UNIV TONGJI | 2015-06-24 | — | — | CN | disclosed |