Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.34 |
| ▸ | GAA | P10253 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | GFER | P55789 | 2/20 | 0.34 |
| ▸ | PARP1 | P09874 | 1/20 | 0.34 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.34 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 5/20 | 0.33 |
| ▸ | RAB9A | P51151 | 5/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.32 |
| ▸ | RELA | Q04206 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30284584 | 0.85 | NPC1 (0.44) | MAPTGAAKMT2APARP1NPC1 | |
| SCHEMBL1553150 | 0.85 | NPC1 (0.44) | MAPTGAAKMT2APARP1NPC1 | |
| SCHEMBL7901284 | 0.84 | RAB9A (0.42) | MAPTALDH1A1GAAKMT2AKDM4E | |
| SCHEMBL29809356 | 0.84 | RAB9A (0.42) | MAPTALDH1A1GAAKMT2AKDM4E | |
| SCHEMBL31612033 | 0.84 | NPC1 (0.43) | MAPTKMT2APARP1NPC1RAB9A | |
| SCHEMBL30633069 | 0.84 | NPC1 (0.43) | MAPTKMT2APARP1NPC1RAB9A | |
| SCHEMBL1356606 | 0.84 | NPC1 (0.43) | MAPTKMT2APARP1NPC1RAB9A | |
| SCHEMBL4206262 | 0.83 | KMT2A (0.50) | ALDH1A1GAAKMT2AKDM4EPARP1 | |
| SCHEMBL16470213 | 0.82 | NPSR1 (0.44) | MAPTALDH1A1GAAKMT2APARP1 | |
| SCHEMBL15251305 | 0.81 | PARP1 (0.33) | MAPTALDH1A1GAAKMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104725359-A | Substituted piperazine compound as well as application method and application thereof | GUANGDONG HEC PHARMACEUTICAL | 2015-06-24 | — | — | CN | disclosed |