Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | PLK1 | P53350 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | PARP1 | P09874 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Quinoline SCHEMBL28013231 | 0.85 | ALDH1A1 (0.61) | ALDH1A1SMN1; SMN2HTTALOX15PLK1 | |
| Quinoline SCHEMBL29290739 | 0.85 | ALDH1A1 (0.49) | ALDH1A1SMN1; SMN2LMNAHTTALOX15 | |
| Quinoline SCHEMBL28013230 | 0.83 | ALDH1A1 (0.46) | ALDH1A1SMN1; SMN2LMNAHTTALOX15 | |
| Quinoline SCHEMBL29290736 | 0.81 | ALDH1A1 (0.44) | ALDH1A1SMN1; SMN2LMNAHTTKDM4E | |
| Quinoline SCHEMBL28819048 | 0.81 | ALDH1A1 (0.44) | ALDH1A1SMN1; SMN2LMNAHTTALOX15 | |
| Quinoline SCHEMBL28169251 | 0.80 | ALDH1A1 (0.68) | ALDH1A1SMN1; SMN2HTTALOX15PLK1 | |
| Quinoline SCHEMBL1287895 | 0.80 | ALDH1A1 (0.74) | ALDH1A1SMN1; SMN2HTTALOX15PLK1 | |
| Quinoline SCHEMBL5272119 | 0.80 | ALDH1A1 (0.74) | ALDH1A1SMN1; SMN2HTTALOX15PLK1 | |
| Quinoline SCHEMBL2201840 | 0.80 | ALDH1A1 (0.74) | ALDH1A1SMN1; SMN2HTTALOX15PLK1 | |
| Quinoline SCHEMBL29290740 | 0.79 | ALDH1A1 (0.52) | ALDH1A1SMN1; SMN2LMNAHTTALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105175392-B | A kind of carboxylic acid compound containing thiophene-structure and amide compound containing thiophene-structure and preparation method thereof | 湖南大学 | 2019-04-19 | — | — | CN | disclosed |
| CN-104496870-A | Catalytic synthesis method of sulfur-containing carboxylic acid compound and sulfur-containing amide compound | UNIV HUNAN | 2015-04-08 | — | — | CN | disclosed |