Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 7/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | APAF1 | O14727 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL2121616 | 0.98 | FDPS (0.44) | FDPSMEN1HSP90AA1KMT2ASMN1; SMN2 | |
| SCHEMBL34844 | 0.98 | — | — | |
| Iodide SCHEMBL1758300 | 0.95 | FDPS (0.45) | FDPSMEN1HSP90AA1KMT2ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL28193505 | 0.95 | FDPS (0.45) | FDPSMEN1HSP90AA1KMT2ASMN1; SMN2 | |
| SCHEMBL28102227 | 0.95 | FDPS (0.45) | FDPSMEN1HSP90AA1KMT2ASMN1; SMN2 | |
| Bromide SCHEMBL2121613 | 0.95 | FDPS (0.45) | FDPSMEN1HSP90AA1KMT2ASMN1; SMN2 | |
| Bromide SCHEMBL557589 | 0.95 | FDPS (0.45) | FDPSMEN1HSP90AA1KMT2ASMN1; SMN2 | |
| Fluoride Ion SCHEMBL1898728 | 0.95 | FDPS (0.45) | FDPSMEN1HSP90AA1KMT2ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL557287 | 0.95 | FDPS (0.45) | FDPSMEN1HSP90AA1KMT2ASMN1; SMN2 | |
| SCHEMBL28209640 | 0.93 | FDPS (0.44) | FDPSMEN1HSP90AA1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104600352-B | Sodium rechargeable battery with the graphite felt for forming air vent channel | SK INNOVATION CO.,LTD. (KR) | 2019-11-01 | — | — | CN | disclosed |
| CN-104600352-A | Sodium secondary battery having graphite felt with pore channels | SK INNOVATION CO LTD | 2015-05-06 | — | — | CN | disclosed |