Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 5/20 | 0.83 |
| ▸ | HTR2B | P41595 | 5/20 | 0.83 |
| ▸ | PNMT | P11086 | 7/20 | 0.76 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.63 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.63 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.63 |
| ▸ | HTR6 | P50406 | 5/20 | 0.55 |
| ▸ | MELK | Q14680 | 1/20 | 0.51 |
| ▸ | MLNR | O43193 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5944522 | 0.86 | PNMT (1.00) | HTR2CHTR2BPNMTADRA2AADRA2B | |
| Hydrochloric Acid SCHEMBL5944489 | 0.85 | PNMT (0.97) | HTR2CHTR2BPNMTADRA2AADRA2B | |
| SCHEMBL15435386 | 0.82 | PNMT (0.77) | HTR2CHTR2BPNMTADRA2AADRA2B | |
| SCHEMBL11483387 | 0.81 | PNMT (0.71) | HTR2CHTR2BPNMTADRA2AADRA2B | |
| Hydrochloric Acid SCHEMBL11475677 | 0.80 | PNMT (0.69) | HTR2CHTR2BPNMTADRA2AADRA2B | |
| SCHEMBL29741628 | 0.78 | PNMT (0.60) | HTR2CPNMTADRA2AADRA2BADRA2C | |
| SCHEMBL420370 | 0.78 | PNMT (0.60) | HTR2CPNMTADRA2AADRA2BADRA2C | |
| SCHEMBL2401511 | 0.78 | PNMT (0.71) | HTR2CHTR2BPNMTADRA2AADRA2B | |
| SCHEMBL29941551 | 0.78 | PNMT (1.00) | HTR2CHTR2BPNMTADRA2AADRA2B | |
| SCHEMBL1487047 | 0.78 | PNMT (1.00) | HTR2CHTR2BPNMTADRA2AADRA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102883607-B | Compounds for the treatment of cancer | GTX INC | 2015-07-22 | — | — | CN | disclosed |
| CN-104592205-A | COMPOUNDS FOR TREATMENT OF CANCER | GTX INC | 2015-05-06 | — | — | CN | disclosed |