Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR9 | Q9NR96 | 5/20 | 0.40 |
| ▸ | TLR8 | Q9NR97 | 5/20 | 0.40 |
| ▸ | TLR7 | Q9NYK1 | 4/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 10/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 10/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 9/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.38 |
| ▸ | QDPR | P09417 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ethoxycarbonyl Group SCHEMBL28291591 | 0.89 | EPHX1 (0.39) | SLC6A2SLC6A4SLC6A3CHRM1DRD2 | |
| SCHEMBL3956097 | 0.83 | SLC6A2 (0.50) | TLR9TLR8TLR7SLC6A2SLC6A4 | |
| Hydrochloric Acid SCHEMBL28061431 | 0.82 | SLC6A2 (0.49) | TLR9TLR8TLR7SLC6A2SLC6A4 | |
| Ethoxycarbonyl Group SCHEMBL27439208 | 0.75 | CYP2A6 (0.46) | CYP2A6 | |
| SCHEMBL12455980 | 0.75 | HTR3A (0.49) | TLR9TLR8TLR7SLC6A2SLC6A4 | |
| Ethoxycarbonyl Group SCHEMBL27597884 | 0.74 | GAA (0.62) | CYP2A6 | |
| Ethoxycarbonyl Group SCHEMBL27650371 | 0.74 | AHR (0.62) | CYP2A6 | |
| Ethoxycarbonyl Group SCHEMBL27447133 | 0.74 | AHR (0.62) | SLC6A2SLC6A4SLC6A3KCNH2CYP2A6 | |
| Ethoxycarbonyl Group SCHEMBL27613736 | 0.74 | AHR (0.62) | CYP2A6 | |
| Ethoxycarbonyl Group SCHEMBL28038686 | 0.74 | CYP2A6 (0.45) | CYP2A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104640853-A | Indole-amide compounds as beta-amyloid inhibitors | HOFFMANN LA ROCHE | 2015-05-20 | — | — | CN | disclosed |