Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | ELANE | P08246 | 1/20 | 0.46 |
| ▸ | ACACB | O00763 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.45 |
| ▸ | TARBP2 | Q15633 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.44 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.44 |
| ▸ | CNR1 | P21554 | 1/20 | 0.44 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.44 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.44 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15114294 | 0.83 | LMNA (0.57) | LMNAACACBSMN1; SMN2ALDH1A1NPSR1 | |
| SCHEMBL9542970 | 0.83 | ELANE (0.57) | ELANEMEN1KMT2A | |
| SCHEMBL18398374 | 0.79 | CYP1A2 (0.48) | LMNAACACBSMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL6201961 | 0.79 | LMNA (0.65) | LMNAACACBSMN1; SMN2KDM4ETDP1 | |
| SCHEMBL4682259 | 0.78 | ELANE (0.53) | LMNAELANEALDH1A1MAPTMEN1 | |
| Methylamine SCHEMBL20393929 | 0.77 | LMNA (0.50) | LMNAELANEACACBSMN1; SMN2ALDH1A1 | |
| SCHEMBL23544689 | 0.76 | NQO1 (0.54) | LMNASMN1; SMN2ALDH1A1NPSR1MAPT | |
| Diphenan SCHEMBL667724 | 0.76 | PLA2G10 (0.58) | LMNAELANEMEN1KMT2A | |
| SCHEMBL8081121 | 0.76 | LMNA (0.53) | LMNAELANEACACBNPSR1MAPT | |
| SCHEMBL30492962 | 0.76 | SIRT2 (0.50) | LMNAACACBSMN1; SMN2ALDH1A1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104961672-A | Synthetic method of tartrate of N-(4-fluorobenzyl)-N-(1-methylpiperidine-4-yl)-N'-(4-isobutoxybenzyl)urea | UNIV SHENYANG PHARMACEUTICAL | 2015-10-07 | — | — | CN | claimed |
| CN-104961672-A | Synthetic method of tartrate of N-(4-fluorobenzyl)-N-(1-methylpiperidine-4-yl)-N'-(4-isobutoxybenzyl)urea | UNIV SHENYANG PHARMACEUTICAL | 2015-10-07 | — | — | CN | disclosed |