SCHEMBL28014472

SCHEMBL28014472

CC(COC(=O)CCC(=O)O)C(C)C(F)(F)F

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EGLN1 Q9GZT9 2/20 0.36
KDM6B O15054 1/20 0.36
KDM5C P41229 1/20 0.36
PHF8 Q9UPP1 1/20 0.36
KDM2A Q9Y2K7 1/20 0.36
LMNA P02545 4/20 0.34
MAPT P10636 1/20 0.34
MMP2 P08253 2/20 0.32
MMP9 P14780 2/20 0.32
MMP12 P39900 2/20 0.32
ALDH1A1 P00352 2/20 0.31
ALKBH5 Q6P6C2 1/20 0.31
SUCNR1 Q9BXA5 1/20 0.31
LPAR1 Q92633 2/20 0.31
GABRP O00591 2/20 0.31
GABRD O14764 2/20 0.31
GABRA1 P14867 2/20 0.31
GABRB1 P18505 2/20 0.31
GABRG2 P18507 2/20 0.31
GABRB3 P28472 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28014471 0.93 MAPT (0.38) LMNAMAPTALDH1A1LPAR1CYP3A4
SCHEMBL28875656 0.80 EGLN1 (0.42) EGLN1KDM6BKDM5CPHF8KDM2A
SCHEMBL28313253 0.78 EGLN1 (0.41) EGLN1KDM6BKDM5CPHF8KDM2A
SCHEMBL28712956 0.76 LMNA (0.34) EGLN1KDM6BKDM5CPHF8KDM2A
SCHEMBL846984 0.75 EGLN1 (0.45) EGLN1KDM6BKDM5CPHF8KDM2A
SCHEMBL27865301 0.75 EGLN1 (0.45) EGLN1KDM6BKDM5CPHF8KDM2A
SCHEMBL1134609 0.74 MAPT (0.58) EGLN1KDM6BKDM5CPHF8KDM2A
SCHEMBL12019084 0.71 NOTUM (0.42) EGLN1KDM6BKDM5CPHF8KDM2A
SCHEMBL13258361 0.71 LMNA (0.45) EGLN1KDM6BKDM5CPHF8KDM2A
SCHEMBL28014426 0.71 MAPT (0.44) LMNAMAPTALDH1A1CYP3A4TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104736627-A Propylene resin composition for retort pouch-packaging film SUN ALLOMER LTD 2015-06-24 CN disclosed