Methane

Methane

SCHEMBL2801477

C.CCc1cc(-c2ccc(N)c(CC)c2)ccc1N

nearest known ligand 0.48

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.48
POLB P06746 4/20 0.48
MAPT P10636 3/20 0.48
KMT2A Q03164 4/20 0.47
MEN1 O00255 3/20 0.47
HSD17B10 Q99714 3/20 0.47
KDM4E B2RXH2 2/20 0.47
MAPK1 P28482 2/20 0.47
HPGD P15428 1/20 0.47
L3MBTL1 Q9Y468 1/20 0.47
CYP3A4 P08684 5/20 0.46
TDP1 Q9NUW8 4/20 0.46
TSHR P16473 3/20 0.46
ALOX15 P16050 1/20 0.41
HSD17B1 P14061 3/20 0.40
GFER P55789 1/20 0.40
RXFP1 Q9HBX9 1/20 0.40
HTT P42858 1/20 0.38
MAP4K1 Q92918 2/20 0.35
ABL1 P00519 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL137005 0.98 ALDH1A1 (0.50) ALDH1A1POLBMAPTKMT2AMEN1
SCHEMBL29404321 0.98 ALDH1A1 (0.50) ALDH1A1POLBMAPTKMT2AMEN1
Hydrochloric Acid SCHEMBL866325 0.95 ALDH1A1 (0.48) ALDH1A1POLBMAPTKMT2AMEN1
Water SCHEMBL28164366 0.95 ALDH1A1 (0.53) ALDH1A1POLBMAPTKMT2AMEN1
Hydrochloric Acid SCHEMBL30932775 0.95 ALDH1A1 (0.48) ALDH1A1POLBMAPTKMT2AMEN1
SCHEMBL310565 0.93 ALDH1A1 (0.47) ALDH1A1POLBMAPTKMT2AMEN1
SCHEMBL29764018 0.93 ALDH1A1 (0.47) ALDH1A1POLBMAPTKMT2AMEN1
SCHEMBL2574764 0.89 ALDH1A1 (0.46) ALDH1A1POLBMAPTKMT2AMEN1
Methane SCHEMBL27799750 0.88 CYP3A4 (0.61) ALDH1A1POLBMAPTKMT2AMEN1
SCHEMBL11511186 0.87 ALDH1A1 (0.68) ALDH1A1POLBMAPTKMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109180941-A A kind of preparation method of eight functional epoxy's POSS resin of hybrid inorganic-organic and the preparation method of carbon fibre reinforced composite 哈尔滨工业大学 2019-01-11 CN claimed
WO-2020032102-A1 NOVEL ONIUM COMPOUND 北興化学工業株式会社 2020-02-13 WO disclosed
CN-109180941-A A kind of preparation method of eight functional epoxy's POSS resin of hybrid inorganic-organic and the preparation method of carbon fibre reinforced composite 哈尔滨工业大学 2019-01-11 CN disclosed
CN-108700836-A METHOD FOR MANUFACTURING LAMINATE AND METHOD FOR MANUFACTURING SEMICONDUCTOR DEVICE 富士胶片株式会社 2018-10-23 CN disclosed
CN-106471089-B Thermokalite producing agent, thermosetting resin composition and application thereof 富士胶片株式会社 2018-10-19 CN disclosed
CN-108191671-A A kind of method for restoring aromatic amine compound and preparing fatty amine 本源精化环保科技有限公司 2018-06-22 CN disclosed
US-20100221646-A1 HOLOGRAPHIC RECORDING MEDIUM KABUSHIKI KAISHA TOSHIBA (JP) 2010-09-02 US disclosed
US-20100020372-A1 HOLOGRAPHIC RECORDING MEDIUM AND OPTICAL INFORMATION RECORDING/REPRODUCING APPARATUS KABUSHIKI KAISHA TOSHIBA 2010-01-28 US disclosed
US-20090053616-A1 HOLOGRAPHIC RECORDING MEDIUM KABUSHIKI KAISHA TOSHIBA 2009-02-26 US disclosed