SCHEMBL28015141

SCHEMBL28015141

NCc1ccccc1-c1ncsc1CO[C]=O

nearest known ligand 0.35

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
DPP4 P27487 3/20 0.35
KDM4E B2RXH2 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5544619 0.81 MAPK14 (0.38) DPP4KDM4E
SCHEMBL5537449 0.81 ADORA2A (0.33) DPP4SMN1; SMN2
SCHEMBL5537646 0.81 NR1H2 (0.38)
SCHEMBL5534779 0.78 FFAR4 (0.36) DPP4
SCHEMBL27574957 0.77 DPP4 (0.41) DPP4
SCHEMBL5538359 0.77 FFAR4 (0.37) KDM4E
SCHEMBL5548160 0.71 MAPT (0.34)
SCHEMBL5543582 0.66 ALDH1A1 (0.47) KDM4ESMN1; SMN2
SCHEMBL5539077 0.62 MAPK14 (0.35) KDM4E
SCHEMBL21092113 0.61 FGFR1 (0.38) KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102532162-B 2,3-dihydro-6-nitroimidazo[2,1-b]oxazoles OTSUKA PHARMA CO LTD 2015-05-27 CN disclosed