Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
| ▸ | BRD2 | P25440 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.31 |
| ▸ | MAPT | P10636 | 4/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | BLM | P54132 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.31 |
| ▸ | STAT6 | P42226 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6010064 | 0.76 | — | — | |
| SCHEMBL1272614 | 0.73 | ALDH1A1 (0.37) | BRD4BRD2ALDH1A1MAPTMEN1 | |
| SCHEMBL7098473 | 0.70 | RXFP1 (0.35) | BRD4ALDH1A1MAPTKMT2AHSD11B1 | |
| SCHEMBL28464884 | 0.70 | TSHR (0.35) | BRD4BRD2ALDH1A1MAPTKMT2A | |
| SCHEMBL11884023 | 0.69 | BRD4 (0.40) | BRD4BRD2ALDH1A1MAPTMEN1 | |
| SCHEMBL761439 | 0.69 | — | — | |
| SCHEMBL30203870 | 0.68 | BRD4 (0.38) | BRD4BRD2ALDH1A1MAPTKMT2A | |
| SCHEMBL2909896 | 0.67 | — | — | |
| SCHEMBL8007247 | 0.67 | ALDH1A1 (0.37) | BRD4BRD2ALDH1A1MAPTMEN1 | |
| SCHEMBL909148 | 0.67 | KMT2A (0.37) | BRD4BRD2ALDH1A1MAPTBLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104619709-A | Imidazopyridine derivatives as modulators of TNF activity | UCB PHARMA SA | 2015-05-13 | — | — | CN | disclosed |