SCHEMBL28015293

SCHEMBL28015293

CC(=O)Oc1cc(OCC(F)(F)F)nn1C

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PKM P14618 1/20 0.48
L3MBTL1 Q9Y468 1/20 0.38
NPC1 O15118 1/20 0.37
ALDH1A1 P00352 3/20 0.37
CYP1A2 P05177 2/20 0.36
RAB9A P51151 1/20 0.36
MAPT P10636 2/20 0.36
JMJD6 Q6NYC1 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
NPSR1 Q6W5P4 1/20 0.36
SCN9A Q15858 3/20 0.34
MEN1 O00255 2/20 0.34
KMT2A Q03164 2/20 0.34
BACE1 P56817 1/20 0.33
CYP2C19 P33261 2/20 0.32
CYP2C9 P11712 1/20 0.32
KDM4E B2RXH2 1/20 0.32
USP2 O75604 1/20 0.32
HPGD P15428 1/20 0.32
HSD17B10 Q99714 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18241096 0.89 PKM (0.51) PKML3MBTL1NPC1ALDH1A1CYP1A2
SCHEMBL13365066 0.77 PKM (0.54) PKML3MBTL1NPC1ALDH1A1CYP1A2
SCHEMBL2362504 0.74 PKM (0.48) PKML3MBTL1NPC1ALDH1A1CYP1A2
SCHEMBL27415472 0.73 PKM (0.45) PKML3MBTL1ALDH1A1CYP1A2MAPT
SCHEMBL27842915 0.72 BACE1 (0.48) NPC1ALDH1A1RAB9AMAPTSMN1; SMN2
SCHEMBL15350128 0.71 PKM (0.43) PKML3MBTL1NPC1ALDH1A1MAPT
SCHEMBL27415470 0.70 MAPK14 (0.44) PKML3MBTL1NPC1ALDH1A1RAB9A
SCHEMBL6215292 0.70 CYP3A4 (0.35) NPC1ALDH1A1RAB9AMAPTSMN1; SMN2
SCHEMBL27682646 0.70 SMN1; SMN2 (0.43) L3MBTL1NPC1ALDH1A1CYP1A2RAB9A
SCHEMBL15350848 0.69 PKM (0.41) PKMNPC1ALDH1A1CYP1A2MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102317263-B Halogen substituted compounds as pesticides BAYER IP GMBH 2015-04-22 CN disclosed