SCHEMBL28015494

SCHEMBL28015494

CCC(C)C(=O)C(=O)O.[NaH]

nearest known ligand 0.57

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
FOLH1 Q04609 2/20 0.33
NAALAD2 Q9Y3Q0 2/20 0.33
GABRR1 P24046 2/20 0.33
FFAR3 O14843 1/20 0.33
CYP1A2 P05177 1/20 0.33
TSHR P16473 1/20 0.33
KDM4E B2RXH2 1/20 0.33
ALDH1A1 P00352 1/20 0.33
RAB9A P51151 1/20 0.33
TP53 P04637 1/20 0.32
ACE2 Q9BYF1 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL188105 0.97
SCHEMBL43232 0.97
SCHEMBL8768172 0.97 FFAR3 (0.35) FOLH1NAALAD2GABRR1FFAR3CYP1A2
SCHEMBL29396747 0.97 FFAR3 (0.35) FOLH1NAALAD2GABRR1FFAR3CYP1A2
SCHEMBL3860250 0.97
SCHEMBL11607991 0.94 FOLH1 (0.33) FOLH1NAALAD2GABRR1FFAR3CYP1A2
L-Lactic Acid SCHEMBL31285806 0.87 TP53 (0.52) FOLH1NAALAD2GABRR1CYP1A2TSHR
SCHEMBL108300 0.82 TSHR (0.41) FOLH1NAALAD2GABRR1FFAR3CYP1A2
2-Oxoisohexanoate SCHEMBL25436317 0.82 CA2 (0.38) ALDH1A1
SCHEMBL3755021 0.82

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105121433-B Antiviral compound, its pharmaceutically acceptable salt or optical isomer, the method for preparing them and the pharmaceutical composition for being used to prevent or treat viral disease for containing the same as active ingredient 韩国化学研究院 2018-01-23 CN disclosed
CN-105121433-A Novel compound, pharmaceutically acceptable salt or optical isomer thereof, method for preparing same, and pharmaceutical composition for prevention or treatment of viral diseases containing same as active ingredient KOREA RES INST CHEM TECH 2015-12-02 CN disclosed
CN-104781213-A Pressure process WZR ceramic solutions GmbH 2015-07-15 CN disclosed