Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 16/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | GMNN | O75496 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CA3 | P07451 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | TYR | P14679 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | CA4 | P22748 | 1/20 | 0.40 |
| ▸ | CA5A | P35218 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8287019 | 0.87 | ESR2 (0.36) | ESR2CYP3A4KDM4EMEN1KMT2A | |
| SCHEMBL21755365 | 0.85 | ESR2 (0.35) | ESR2CYP3A4KDM4EMEN1KMT2A | |
| SCHEMBL18257871 | 0.83 | ESR2 (0.40) | ESR2CYP3A4KDM1AESR1CYP2C9 | |
| SCHEMBL18257865 | 0.83 | ESR2 (0.40) | ESR2CYP3A4KDM1AESR1CYP2C9 | |
| SCHEMBL18257851 | 0.82 | ESR2 (0.33) | ESR2CYP3A4KDM4EMEN1KMT2A | |
| SCHEMBL18257838 | 0.79 | ESR2 (0.39) | ESR2ALDH1A1HSD17B10KDM1AESR1 | |
| SCHEMBL2720135 | 0.77 | ESR2 (0.48) | ESR2CYP3A4KDM4EMEN1KMT2A | |
| SCHEMBL17754284 | 0.76 | ESR2 (0.35) | ESR2CYP3A4KDM4EMEN1KMT2A | |
| SCHEMBL6755897 | 0.75 | ESR2 (0.42) | ESR2CYP3A4KDM4EMEN1KMT2A | |
| SCHEMBL2717925 | 0.72 | KDM1A (0.38) | ESR2CYP3A4KDM1AESR1CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102532162-B | 2,3-dihydro-6-nitroimidazo[2,1-b]oxazoles | OTSUKA PHARMA CO LTD | 2015-05-27 | — | — | CN | disclosed |