SCHEMBL17754284

SCHEMBL17754284

OC1=CCC(c2ccc(O)cc2)C=C1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR2 Q92731 14/20 0.35
KDM1A O60341 1/20 0.33
ESR1 P03372 3/20 0.32
CYP3A4 P08684 2/20 0.32
CYP2C9 P11712 1/20 0.32
KDM4E B2RXH2 1/20 0.32
MEN1 O00255 1/20 0.32
NPC1 O15118 1/20 0.32
CA12 O43570 1/20 0.32
GMNN O75496 1/20 0.32
ALDH1A1 P00352 1/20 0.32
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32
LMNA P02545 1/20 0.32
CA3 P07451 1/20 0.32
MAPT P10636 1/20 0.32
TYR P14679 1/20 0.32
HPGD P15428 1/20 0.32
ALOX15 P16050 1/20 0.32
NFKB1 P19838 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19114458 0.83 ESR1 (0.45) ESR2KDM1AESR1MEN1KMT2A
SCHEMBL2717925 0.79 KDM1A (0.38) ESR2KDM1AESR1CYP3A4CYP2C9
SCHEMBL24619865 0.77 ESR2 (0.33) ESR2ALDH1A1MAPTKMT2A
SCHEMBL23505681 0.77 ESR2 (0.33) ESR2
SCHEMBL19338351 0.77 CA12 (0.35) ESR2CA12CA1CA2CA3
SCHEMBL14747878 0.75 ESR1 (0.39) ESR2ESR1CYP3A4CYP2C9KDM4E
SCHEMBL4220882 0.71 ESR2 (0.38) ESR2ESR1MEN1ALDH1A1MAPT
SCHEMBL22561003 0.70 ESR2 (0.49) ESR2KDM4EMEN1NPC1CA12
SCHEMBL12158788 0.70 ESR1 (0.45) ESR2ESR1CYP3A4KDM4EMEN1
SCHEMBL8287019 0.69 ESR2 (0.36) ESR2KDM1AESR1CYP3A4CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11911482-B2 Self assembling protein nanoparticles as carrier molecules THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2024-02-27 US disclosed
EP-4242265-A1 RESIN COMPOSITION, COATING FILM USING SAME, AND ELECTROLYTE MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2023-09-13 EP disclosed
EP-4204435-A1 SELF-ASSEMBLING PROTEIN NANOPARTICLES AS CARRIER MOLECULES The Regents of University of California (US) 2023-07-05 EP disclosed
US-20220062430-A1 Self Assembling Protein Nanoparticles as Carrier Molecules THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2022-03-03 US disclosed
EP-2832759-B1 EPOXY RESIN, METHOD FOR PRODUCING EPOXY RESIN, EPOXY RESIN COMPOSITION, CURED PRODUCT THEREOF, AND HEAT-DISSIPATING RESIN MATERIAL DAINIPPON INK & CHEMICALS (JP) 2017-03-15 EP disclosed
US-20160355939-A1 POLARIZATION STABILIZER ADDITIVE FOR ELECTROPLATING LAM RESEARCH CORPORATION 2016-12-08 US disclosed
US-20160137921-A1 POLYMERIZABLE COMPOUND, AND LIQUID CRYSTAL COMPOSITION PRODUCED USING SAME DIC CORPORATION (JP) 2016-05-19 US disclosed
US-20160137921-A1 POLYMERIZABLE COMPOUND, AND LIQUID CRYSTAL COMPOSITION PRODUCED USING SAME DIC CORPORATION (JP) 2016-05-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160137921-A1 POLYMERIZABLE COMPOUND, AND LIQUID CRYSTAL COMPOSITION PRODUCED USING SAME RCC1, LPXN, SMC4 ESR2 4850/4885KDM1A 2146/4885ESR1 4794/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.