Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DBH | P09172 | 6/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | UBE2N | P61088 | 1/20 | 0.42 |
| ▸ | HSP90B1 | P14625 | 1/20 | 0.42 |
| ▸ | TRAP1 | Q12931 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | DAO | P14920 | 1/20 | 0.41 |
| ▸ | APAF1 | O14727 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10978060 | 0.79 | DBH (0.68) | DBHKMT2ASMN1; SMN2LMNAHTT | |
| SCHEMBL8583692 | 0.78 | DBH (0.45) | DBHPOLBALDH1A1TP53CYP1A2 | |
| SCHEMBL7690163 | 0.78 | DBH (0.45) | DBHKMT2ASMN1; SMN2POLBALDH1A1 | |
| SCHEMBL4101771 | 0.78 | DBH (0.62) | DBHKMT2ASMN1; SMN2HTTPOLB | |
| SCHEMBL27281887 | 0.75 | CNOT7 (0.43) | DBHPOLBALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL21382645 | 0.74 | CYP11B1 (0.44) | DBHPOLBDAOALDH1A1CYP1A2 | |
| SCHEMBL6156795 | 0.74 | CMA1 (0.53) | KMT2ALMNAGAADAOALDH1A1 | |
| SCHEMBL7325261 | 0.74 | PDE4B (0.57) | DBHKMT2AGAASIGMAR1ALDH1A1 | |
| SCHEMBL27629494 | 0.72 | KDM4E (0.49) | DBHKMT2ASMN1; SMN2LMNAPOLB | |
| SCHEMBL11613138 | 0.70 | KMT2A (0.47) | DBHKMT2ASMN1; SMN2LMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102532162-B | 2,3-dihydro-6-nitroimidazo[2,1-b]oxazoles | OTSUKA PHARMA CO LTD | 2015-05-27 | — | — | CN | disclosed |