Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 3/20 | 0.39 |
| ▸ | RORC | P51449 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | JAK2 | O60674 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4767667 | 0.86 | KMT2A (0.42) | TP53RORCALDH1A1TSHRNPC1 | |
| SCHEMBL5881182 | 0.81 | TP53 (0.42) | TP53ALDH1A1GLATSHRHTR1A | |
| SCHEMBL11466075 | 0.78 | TP53 (0.44) | TP53ALDH1A1GLATSHRTRPM8 | |
| SCHEMBL5167326 | 0.78 | HTR1A (0.37) | TP53ALDH1A1HTR1ANPSR1 | |
| SCHEMBL4773995 | 0.77 | TSHR (0.46) | TP53ALDH1A1TSHRNPC1JAK2 | |
| SCHEMBL5515003 | 0.77 | TP53 (0.49) | TP53ALDH1A1TSHRTRPM8SMN1; SMN2 | |
| SCHEMBL29009675 | 0.77 | TP53 (0.41) | TP53RORCALDH1A1GLATSHR | |
| SCHEMBL5166937 | 0.76 | HTR1A (0.36) | TP53TSHRHTR1ACYP3A4 | |
| SCHEMBL5166923 | 0.75 | HTR1A (0.35) | TP53ALDH1A1TSHRHTR1ANPC1 | |
| SCHEMBL11463874 | 0.74 | SLC6A2 (0.40) | TP53ALDH1A1SMN1; SMN2KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102532162-B | 2,3-dihydro-6-nitroimidazo[2,1-b]oxazoles | OTSUKA PHARMA CO LTD | 2015-05-27 | — | — | CN | disclosed |