Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | SPHK1 | Q9NYA1 | 4/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
| ▸ | BRD2 | P25440 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10804538 | 0.76 | PSEN1 (0.43) | L3MBTL1TSHR | |
| SCHEMBL28187076 | 0.73 | ACHE (0.43) | TSHR | |
| SCHEMBL14012780 | 0.72 | POLB (0.47) | POLBL3MBTL1LMNASPHK1BRD4 | |
| SCHEMBL14401842 | 0.72 | POLB (0.47) | POLBL3MBTL1LMNASPHK1BRD4 | |
| SCHEMBL14295187 | 0.72 | POLB (0.47) | POLBL3MBTL1LMNASPHK1BRD4 | |
| SCHEMBL24970873 | 0.71 | POLB (0.39) | POLBL3MBTL1SPHK1RAB9ASPHK2 | |
| SCHEMBL15521588 | 0.70 | POLB (0.41) | POLBL3MBTL1SPHK1SPHK2 | |
| SCHEMBL25361796 | 0.70 | POLB (0.41) | POLBL3MBTL1SPHK1SPHK2 | |
| SCHEMBL28235216 | 0.70 | POLB (0.37) | POLBL3MBTL1LMNASPHK1RAB9A | |
| SCHEMBL8150213 | 0.69 | TP53 (0.44) | POLBTSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102448458-B | Methods and compositions for treating flaviviridae virus infections | UNIV LELAND STANFORD JUNIOR | 2015-07-22 | — | — | CN | disclosed |