SCHEMBL28015759

SCHEMBL28015759

CNC(=O)OC1CCN(CC2(C)CO2)CC1

nearest known ligand 0.38

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
CHRM3 P20309 12/20 0.38
CHRM1 P11229 1/20 0.36
BCHE P06276 4/20 0.36
CARM1 Q86X55 1/20 0.35
PRMT6 Q96LA8 1/20 0.35
MAOB P27338 1/20 0.34
EPHX1 P07099 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28795878 0.75 TSHR (0.37) EPHX1
SCHEMBL20742436 0.73 CHRM3 (0.53) CHRM3CHRM1BCHECARM1PRMT6
SCHEMBL5540543 0.72 SMN1; SMN2 (0.37)
SCHEMBL5540549 0.72 SMN1; SMN2 (0.37)
SCHEMBL28999358 0.72 CHRM1 (0.44) CHRM1EPHX1
SCHEMBL30916849 0.71 CHRM3 (0.49) CHRM3CHRM1
SCHEMBL22892755 0.71 OPRL1 (0.42) CHRM3CHRM1BCHECARM1PRMT6
SCHEMBL103736 0.70
SCHEMBL10810342 0.70 EPHX1 (0.47) CHRM1BCHEEPHX1
SCHEMBL6010839 0.70 MAPT (0.50)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102532162-B 2,3-dihydro-6-nitroimidazo[2,1-b]oxazoles OTSUKA PHARMA CO LTD 2015-05-27 CN disclosed