SCHEMBL28015853

SCHEMBL28015853

CCOc1oc(C(=O)O)nc1C

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 3/20 0.36
L3MBTL1 Q9Y468 2/20 0.36
NPC1 O15118 2/20 0.36
RAB9A P51151 2/20 0.36
POLB P06746 1/20 0.36
MAPK1 P28482 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
MME P08473 1/20 0.35
MAPT P10636 3/20 0.34
KDM4E B2RXH2 6/20 0.34
ALDH1A1 P00352 5/20 0.34
HPGD P15428 5/20 0.34
HSD17B10 Q99714 3/20 0.34
CYP1A2 P05177 1/20 0.34
TSHR P16473 1/20 0.34
BRD4 O60885 1/20 0.34
BRD2 P25440 1/20 0.34
CREBBP Q92793 1/20 0.34
KMT2A Q03164 1/20 0.32
MITF O75030 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28350765 0.84 CYP1A2 (0.40) SMN1; SMN2L3MBTL1NPC1RAB9AMAPK1
SCHEMBL8027263 0.84 ALDH1A1 (0.37) SMN1; SMN2NPC1RAB9APOLBMAPK1
SCHEMBL27829067 0.83 ALDH1A1 (0.43) SMN1; SMN2NPC1RAB9ATDP1KDM4E
SCHEMBL28350922 0.83 MME (0.36) SMN1; SMN2L3MBTL1NPC1RAB9APOLB
SCHEMBL28350979 0.79 MEN1 (0.32) SMN1; SMN2L3MBTL1RAB9AMAPK1MME
SCHEMBL28347719 0.78 MAPT (0.50) SMN1; SMN2NPC1RAB9AMAPK1MAPT
SCHEMBL28347792 0.77 POLB (0.42) SMN1; SMN2L3MBTL1POLBMAPK1TDP1
SCHEMBL28347892 0.75 ALDH1A1 (0.42) L3MBTL1NPC1RAB9APOLBMAPK1
SCHEMBL2202683 0.71 KDM4E (0.38) SMN1; SMN2L3MBTL1NPC1RAB9APOLB
SCHEMBL2616837 0.70 KDM4E (0.38) SMN1; SMN2RAB9APOLBTDP1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120923437-A Method for preparing oxazole carboxylic acid ester and method for preparing 4-methyl-5-ethoxy-2-oxazolic acid ethyl ester 万华化学集团股份有限公司 2025-11-11 CN disclosed
CN-109836374-B Environment-friendly preparation method of vitamin B6 新发药业有限公司 2020-10-30 CN disclosed
CN-110862344-A 1/20 aquo-vitamin B6 compound 海南顿斯医药科技有限公司 2020-03-06 CN disclosed
CN-104628633-A Synthetic method of vitamin B6 DAFENG HEGNO PHARMACEUTICALS CO LTD 2015-05-20 CN disclosed