Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR5 | Q9H228 | 12/20 | 0.38 |
| ▸ | S1PR1 | P21453 | 6/20 | 0.38 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.32 |
| ▸ | IDO1 | P14902 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2800592 | 0.87 | KDM4E (0.41) | S1PR5S1PR1AVPR1AKDM4EALDH1A1 | |
| SCHEMBL2799589 | 0.79 | KDM4E (0.41) | S1PR5KDM4EALDH1A1HPGDKMT2A | |
| SCHEMBL2803207 | 0.75 | NPC1 (0.41) | AVPR1AKDM4EALDH1A1HPGDKMT2A | |
| SCHEMBL2801299 | 0.74 | AVPR1A (0.47) | AVPR1AKDM4EALDH1A1HPGDNPC1 | |
| SCHEMBL2799919 | 0.73 | CCNA2 (0.40) | KDM4EALDH1A1HPGDKMT2AMEN1 | |
| SCHEMBL2801052 | 0.73 | ALDH1A1 (0.37) | KDM4EALDH1A1HPGDKMT2AMEN1 | |
| SCHEMBL2803128 | 0.73 | BRAF (0.37) | KDM4EALDH1A1HPGDKMT2AMEN1 | |
| SCHEMBL2798480 | 0.73 | ALDH1A1 (0.37) | KDM4EALDH1A1HPGDKMT2AMEN1 | |
| SCHEMBL16390962 | 0.72 | NPC1 (0.38) | KDM4EALDH1A1HPGDNPC1RAB9A | |
| SCHEMBL2801509 | 0.72 | KDM4E (0.41) | AVPR1AKDM4EALDH1A1HPGDNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2206714-A1 | AGENT FOR PREVENTION AND/OR TREATMENT OF SKIN DISEASES | Kyowa Hakko Kirin Co., Ltd. (JP) | 2010-07-14 | — | — | EP | disclosed |