SCHEMBL28016131

SCHEMBL28016131

CC(=O)CC(=O)Cc1ccccc1.[Mn]

nearest known ligand 0.52

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
CES1 P23141 2/20 0.52
CES2 O00748 1/20 0.52
AKR1B1 P15121 1/20 0.52
ALDH1A1 P00352 4/20 0.50
MEN1 O00255 2/20 0.50
KMT2A Q03164 2/20 0.50
HDAC8 Q9BY41 1/20 0.50
HDAC6 Q9UBN7 1/20 0.50
TDP1 Q9NUW8 1/20 0.49
L3MBTL1 Q9Y468 1/20 0.49
EPHX2 P34913 1/20 0.47
KDM4E B2RXH2 2/20 0.45
CNR2 P34972 1/20 0.44
HPGD P15428 1/20 0.44
TSHR P16473 1/20 0.44
FNTA P49354 1/20 0.44
FNTB P49356 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1535041 0.98 CES1 (0.54) CES1CES2AKR1B1ALDH1A1MEN1
SCHEMBL27976185 0.96 CES1 (0.52) CES1CES2AKR1B1ALDH1A1MEN1
SCHEMBL30293214 0.96 CES1 (0.52) CES1CES2AKR1B1ALDH1A1MEN1
SCHEMBL31412115 0.96 CES1 (0.52) CES1CES2AKR1B1ALDH1A1MEN1
SCHEMBL28533260 0.96 CES1 (0.52) CES1CES2AKR1B1ALDH1A1MEN1
SCHEMBL28232885 0.96 CES1 (0.52) CES1CES2AKR1B1ALDH1A1MEN1
SCHEMBL8748892 0.96 CES1 (0.52) CES1CES2AKR1B1ALDH1A1MEN1
Cesium SCHEMBL9566054 0.96 CES1 (0.52) CES1CES2AKR1B1ALDH1A1MEN1
Acetoacetic Acid SCHEMBL8026144 0.88 AKR1B1 (0.54) CES1CES2AKR1B1ALDH1A1MEN1
SCHEMBL28073965 0.86 CES2 (0.57) CES1CES2AKR1B1ALDH1A1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108346497-A A kind of magnetic nanoparticle and its flowing preparation method and system 北京万德高科技发展有限公司 2018-07-31 CN disclosed
CN-104740654-B The method of magnetic nanoparticle magnetic resonance contrast agent and enhancing magnetic nanoparticle relaxation rate 中国科学院化学研究所 2017-12-29 CN disclosed
CN-104740654-A Magnetic nanoparticle magnetic resonance contrast agent and magnetic nanoparticle relaxation rate enhancing method CHINESE ACAD INST CHEMISTRY 2015-07-01 CN disclosed