SCHEMBL28016178

SCHEMBL28016178

Nc1ccccc1-c1ccccc1-c1ccc2ccccc2c1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GSTP1 P09211 1/20 0.53
ALDH1A1 P00352 4/20 0.52
L3MBTL1 Q9Y468 1/20 0.52
DHFR P00374 2/20 0.50
KDM4E B2RXH2 2/20 0.49
HDAC4 P56524 1/20 0.49
HDAC2 Q92769 1/20 0.49
HDAC8 Q9BY41 1/20 0.49
CYP1A2 P05177 1/20 0.47
ADORA2A P29274 2/20 0.46
ADORA1 P30542 2/20 0.46
SRC P12931 1/20 0.46
HSD17B10 Q99714 2/20 0.45
CYP3A4 P08684 1/20 0.45
NPC1 O15118 1/20 0.44
AR P10275 1/20 0.44
MAPT P10636 1/20 0.44
NFKB1 P19838 1/20 0.44
RAB9A P51151 1/20 0.44
GFER P55789 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL557231 0.92 GSTP1 (0.57) GSTP1ALDH1A1L3MBTL1DHFRKDM4E
SCHEMBL31189123 0.92 GSTP1 (0.57) GSTP1ALDH1A1L3MBTL1DHFRKDM4E
SCHEMBL31189124 0.92 GSTP1 (0.57) GSTP1ALDH1A1L3MBTL1DHFRKDM4E
SCHEMBL30491158 0.85 GSTP1 (0.70) GSTP1ALDH1A1DHFRKDM4EHDAC4
SCHEMBL28508645 0.85 GSTP1 (0.70) GSTP1ALDH1A1DHFRKDM4EHDAC4
SCHEMBL8207542 0.82 GSTP1 (0.52) GSTP1ALDH1A1DHFRKDM4EHDAC4
SCHEMBL22517276 0.82 GSTP1 (0.55) GSTP1ALDH1A1DHFRKDM4EHDAC4
SCHEMBL16812110 0.81 GSTP1 (0.60) GSTP1ALDH1A1DHFRKDM4EHDAC4
SCHEMBL18903051 0.81 ALDH1A1 (0.52) GSTP1ALDH1A1DHFRKDM4EHDAC4
SCHEMBL17402596 0.81 GSTP1 (0.50) GSTP1ALDH1A1L3MBTL1DHFRKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104629721-A Organic luminescent material with excellent performance and preparation method thereof JILIN OPTICAL & ELECTRONIC MATERIALS CO LTD 2015-05-20 CN disclosed