Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | FLT3 | P36888 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 3/20 | 0.36 |
| ▸ | CA9 | Q16790 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.35 |
| ▸ | GAA | P10253 | 3/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | GLA | P06280 | 2/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
| ▸ | ELANE | P08246 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7448691 | 0.80 | KDM4E (0.37) | KDM4EGAAGLAMAPTALDH1A1 | |
| SCHEMBL28980176 | 0.79 | KMT2A (0.43) | LMNAKDM4EGAAPOLBGLA | |
| SCHEMBL6754107 | 0.77 | LMNA (0.43) | LMNAFLT3CA12CA9KDM4E | |
| SCHEMBL27523196 | 0.75 | KDM4E (0.38) | LMNAFLT3CA12CA9KDM4E | |
| SCHEMBL27487969 | 0.75 | KMT2A (0.44) | LMNAFLT3CA12CA9KDM4E | |
| SCHEMBL1249499 | 0.75 | KDM4E (0.39) | LMNAFLT3CA12CA9KDM4E | |
| SCHEMBL17077645 | 0.75 | CYP2E1 (0.35) | LMNAFLT3CA12CA9KDM4E | |
| SCHEMBL27669264 | 0.74 | NQO2 (0.41) | LMNAKDM4ECYP19A1ALDH1A1HPGD | |
| SCHEMBL6229622 | 0.73 | TDP1 (0.51) | LMNAKDM4EGAAPOLBTDP1 | |
| SCHEMBL27839207 | 0.73 | LMNA (0.36) | LMNAFLT3CA12CA9KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104540835-A | Imidazothiadiazole derivatives as protease activated receptor 4 (par4) inhibitors for treating platelet aggregation | BRISTOL MYERS SQUIBB CO | 2015-04-22 | — | — | CN | disclosed |