Octane

Octane

SCHEMBL28016307

C=Cn1ccnc1.CCCCCCCC

nearest known ligand 0.52

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TBXAS1 P24557 4/20 0.52
CYP3A4 P08684 2/20 0.37
CYP2D6 P10635 2/20 0.37
CYP1A2 P05177 1/20 0.36
CYP19A1 P11511 1/20 0.36
CYP2C9 P11712 1/20 0.36
CYP2C19 P33261 1/20 0.36
TSHR P16473 2/20 0.35
TBXA2R P21731 2/20 0.33
QPCT Q16769 2/20 0.32
NFKB1 P19838 1/20 0.32
HSD17B10 Q99714 1/20 0.32
QPCTL Q9NXS2 1/20 0.32
PLA2G4A P47712 1/20 0.32
CYP17A1 P05093 1/20 0.31
THRB P10828 1/20 0.31
MAPK1 P28482 1/20 0.30
HTT P42858 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30
HSP90AA1 P07900 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Nonane SCHEMBL27924832 1.00 TBXAS1 (0.52) TBXAS1CYP3A4CYP2D6CYP1A2CYP19A1
Dodecane SCHEMBL15538248 0.98 TBXAS1 (0.50) TBXAS1CYP3A4CYP2D6CYP1A2CYP19A1
Octane SCHEMBL15537557 0.98 TBXAS1 (0.50) TBXAS1CYP3A4CYP2D6CYP1A2CYP19A1
Octane SCHEMBL15537556 0.98 TBXAS1 (0.50) TBXAS1CYP3A4CYP2D6CYP1A2CYP19A1
Dodecane SCHEMBL15538245 0.98 TBXAS1 (0.50) TBXAS1CYP3A4CYP2D6CYP1A2CYP19A1
Hexane SCHEMBL27685943 0.98 TBXAS1 (0.48) TBXAS1CYP3A4CYP2D6CYP1A2CYP19A1
Hexane SCHEMBL28818270 0.96 TBXAS1 (0.47) TBXAS1CYP3A4CYP2D6CYP1A2CYP19A1
SCHEMBL29153550 0.92 TBXAS1 (0.45) TBXAS1CYP3A4CYP2D6CYP1A2CYP19A1
SCHEMBL29022436 0.92 TBXAS1 (0.45) TBXAS1CYP3A4CYP2D6CYP1A2CYP19A1
Butane SCHEMBL28016962 0.90 TBXAS1 (0.38) TBXAS1CYP3A4CYP2D6CYP1A2CYP19A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104689807-A Am imidazole dicationic ionic liquid hydrophilic interaction chromatography stationary phase, and preparation and applications thereof DALIAN CHEMICAL PHYSICS INST 2015-06-10 CN claimed
CN-104689807-A Am imidazole dicationic ionic liquid hydrophilic interaction chromatography stationary phase, and preparation and applications thereof DALIAN CHEMICAL PHYSICS INST 2015-06-10 CN disclosed