Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CHRM5 | P08912 | 3/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.35 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.35 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL154200 | 0.90 | LMNA (0.55) | LMNAMAPTPOLBHRH3MEN1 | |
| SCHEMBL64903 | 0.90 | — | — | |
| SCHEMBL18228041 | 0.90 | — | — | |
| SCHEMBL64890 | 0.87 | — | — | |
| SCHEMBL18000680 | 0.87 | — | — | |
| SCHEMBL27529972 | 0.83 | LMNA (0.48) | LMNAMAPTPOLBHRH3MEN1 | |
| Ethane SCHEMBL23930405 | 0.82 | LMNA (0.52) | LMNAMAPTPOLBHRH3MEN1 | |
| SCHEMBL16097879 | 0.82 | — | — | |
| Acetonitrile SCHEMBL15093668 | 0.80 | LMNA (0.50) | LMNAMAPTPOLBHRH3MEN1 | |
| SCHEMBL22691920 | 0.79 | POLB (0.56) | LMNAMAPTPOLBHRH3MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104684893-B | Asymmetric auxiliary group | 日本波涛生命科学公司 | 2016-10-26 | — | — | CN | disclosed |
| CN-104661664-A | Chiral control | WAVE LIFE SCIENCES PTY LTD | 2015-05-27 | — | — | CN | disclosed |