SCHEMBL28016376

SCHEMBL28016376

Cc1ccc(S(=O)(=O)c2ccc(C)cc2C=Cc2ccccc2)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR2A P28223 1/20 0.45
HTR2C P28335 1/20 0.45
KCNH2 Q12809 1/20 0.45
ALDH1A1 P00352 5/20 0.44
KDM4E B2RXH2 3/20 0.44
SMN1; SMN2 Q16637 2/20 0.44
LMNA P02545 1/20 0.44
MEN1 O00255 1/20 0.44
KMT2A Q03164 1/20 0.44
HTT P42858 2/20 0.43
GAA P10253 2/20 0.43
L3MBTL1 Q9Y468 1/20 0.43
PPARG P37231 2/20 0.42
NPSR1 Q6W5P4 1/20 0.42
RXFP1 Q9HBX9 1/20 0.42
NFE2L2 Q16236 1/20 0.41
RAD51 Q06609 1/20 0.40
TUBB4A P04350 1/20 0.40
TUBB P07437 1/20 0.40
TUBA3C P0DPH7 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28017039 0.88 HTR2A (0.48) HTR2AHTR2CKCNH2ALDH1A1KDM4E
SCHEMBL28016378 0.88 PPARG (0.48) HTR2AHTR2CKCNH2ALDH1A1KDM4E
SCHEMBL28016377 0.83 HTT (0.43) HTR2AHTR2CKCNH2ALDH1A1SMN1; SMN2
SCHEMBL8168808 0.82 SMN1; SMN2 (0.46) ALDH1A1KDM4ESMN1; SMN2LMNAMEN1
SCHEMBL28016380 0.81 HTR2A (0.60) HTR2AHTR2CKCNH2NFE2L2
SCHEMBL28017032 0.81 HTR2A (0.47) HTR2AHTR2CKCNH2ALDH1A1KDM4E
SCHEMBL3162451 0.76 TSHR (0.57) HTR2AHTR2CKCNH2LMNAKMT2A
SCHEMBL3162463 0.76 TSHR (0.57) HTR2AHTR2CKCNH2LMNAKMT2A
SCHEMBL9620555 0.74 GAA (0.57) ALDH1A1KDM4ESMN1; SMN2LMNAMEN1
SCHEMBL28249819 0.73 HSD11B1 (0.51) HTR2AHTR2CKCNH2ALDH1A1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104592086-A Method for preparing indole compound through copper salt catalysis UNIV TAIZHOU 2015-05-06 CN disclosed