SCHEMBL28016381

SCHEMBL28016381

Nc1ccc(Sc2cc(Sc3ccc(N)cc3)cc(Sc3ccc(N)cc3)c2)cc1

nearest known ligand 0.82

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 3/20 0.82
TSHR P16473 1/20 0.82
MAPK1 P28482 1/20 0.82
PDE7A Q13946 6/20 0.52
MAPT P10636 4/20 0.52
MEN1 O00255 3/20 0.52
KMT2A Q03164 3/20 0.52
ANXA2 P07355 1/20 0.50
S100A10 P60903 1/20 0.50
ALDH1A1 P00352 2/20 0.44
TDP1 Q9NUW8 2/20 0.44
KDM4E B2RXH2 2/20 0.44
MCL1 Q07820 1/20 0.43
KDM1A O60341 1/20 0.42
NR1H2 P55055 1/20 0.41
TP53 P04637 1/20 0.40
PDE7B Q9NP56 1/20 0.39
HTT P42858 1/20 0.38
HPGD P15428 2/20 0.37
CYP2C19 P33261 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9647766 0.91 CYP3A4 (1.00) CYP3A4TSHRMAPK1PDE7AMAPT
SCHEMBL9649049 0.91 CYP3A4 (1.00) CYP3A4TSHRMAPK1PDE7AMAPT
SCHEMBL10813732 0.91 CYP3A4 (1.00) CYP3A4TSHRMAPK1PDE7AMAPT
SCHEMBL9485453 0.91 CYP3A4 (1.00) CYP3A4TSHRMAPK1PDE7AMAPT
SCHEMBL9485438 0.91 CYP3A4 (1.00) CYP3A4TSHRMAPK1PDE7AMAPT
SCHEMBL9647870 0.91 CYP3A4 (1.00) CYP3A4TSHRMAPK1PDE7AMAPT
SCHEMBL1098379 0.91 CYP3A4 (1.00) CYP3A4TSHRMAPK1PDE7AMAPT
4,4'-Thiodianiline SCHEMBL49068 0.91 CYP3A4 (1.00) CYP3A4TSHRMAPK1PDE7AMAPT
SCHEMBL9649030 0.91 CYP3A4 (1.00) CYP3A4TSHRMAPK1PDE7AMAPT
4,4'-Thiodianiline SCHEMBL8646940 0.88 CYP3A4 (0.93) CYP3A4TSHRMAPK1PDE7AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113477235-B Coimide aerogel block adsorbing material with micropores and preparation method thereof 大连理工大学 2023-04-14 CN claimed
CN-113477235-B Coimide aerogel block adsorbing material with micropores and preparation method thereof 大连理工大学 2023-04-14 CN disclosed
CN-104592069-A 1,3,5-tris(4-aminophenylmercapto)benzene as well as preparation method and application thereof UNIV JILIN 2015-05-06 CN disclosed
CN-104592069-A 1,3,5-tris(4-aminophenylmercapto)benzene as well as preparation method and application thereof UNIV JILIN 2015-05-06 CN disclosed