SCHEMBL1098379

SCHEMBL1098379

Nc1ccc(Sc2ccc(Sc3ccc(N)cc3)cc2)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 4/20 1.00
MAPK1 P28482 2/20 1.00
TSHR P16473 2/20 1.00
MAPT P10636 3/20 0.58
MEN1 O00255 2/20 0.58
KMT2A Q03164 2/20 0.58
PDE7A Q13946 2/20 0.52
ALDH1A1 P00352 5/20 0.50
TDP1 Q9NUW8 3/20 0.50
KDM4E B2RXH2 1/20 0.50
ANXA2 P07355 1/20 0.50
S100A10 P60903 1/20 0.50
NR1H2 P55055 1/20 0.47
TP53 P04637 1/20 0.47
KDM1A O60341 1/20 0.46
MCL1 Q07820 1/20 0.42
ALOX15 P16050 2/20 0.42
ACHE P22303 1/20 0.42
CA3 P07451 1/20 0.42
THRB P10828 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9649049 1.00 CYP3A4 (1.00) CYP3A4MAPK1TSHRMAPTMEN1
4,4'-Thiodianiline SCHEMBL49068 1.00 CYP3A4 (1.00) CYP3A4MAPK1TSHRMAPTMEN1
SCHEMBL10813732 1.00 CYP3A4 (1.00) CYP3A4MAPK1TSHRMAPTMEN1
SCHEMBL9647870 1.00 CYP3A4 (1.00) CYP3A4MAPK1TSHRMAPTMEN1
SCHEMBL9647766 1.00 CYP3A4 (1.00) CYP3A4MAPK1TSHRMAPTMEN1
SCHEMBL9485453 1.00 CYP3A4 (1.00) CYP3A4MAPK1TSHRMAPTMEN1
SCHEMBL9485438 1.00 CYP3A4 (1.00) CYP3A4MAPK1TSHRMAPTMEN1
SCHEMBL9649030 1.00 CYP3A4 (1.00) CYP3A4MAPK1TSHRMAPTMEN1
4,4'-Thiodianiline SCHEMBL8646940 0.97 CYP3A4 (0.93) CYP3A4MAPK1TSHRMAPTMEN1
SCHEMBL9153502 0.91 CYP3A4 (0.82) CYP3A4MAPK1TSHRMAPTMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 195 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0213573-B1 CRYSTALLINE POLYIMIDES CONTAINING CUMULATIVE PHENYLENE SULFIDE UNITS GENERAL ELECTRIC COMPANY (US) 1991-11-21 EP claimed
EP-0268091-A1 Crystalline polyimides containing cumulative phenylene sulfide units GENERAL ELECTRIC COMPANY (US) 1988-05-25 EP claimed
US-4716216-A HIGH SOLVENT RESISTANCE GENERAL ELECTRIC COMPANY (US) 1987-12-29 US claimed
EP-0213573-A2 Crystalline polyimides containing cumulative phenylene sulfide units GENERAL ELECTRIC COMPANY (US) 1987-03-11 EP claimed
JP-62151424-A None JP disclosed
JP-2308856-A None JP disclosed
JP-63069828-A None JP disclosed
JP-3221559-A None JP disclosed
US-11806661-B2 Polymer and method for producing the same, gas separation membrane, gas separation module, and gas separation apparatus using the polymer, and m-phenylenediamine compound FUJIFILM CORPORATION (JP) 2023-11-07 US disclosed
US-11806661-B2 Polymer and method for producing the same, gas separation membrane, gas separation module, and gas separation apparatus using the polymer, and m-phenylenediamine compound FUJIFILM CORPORATION (JP) 2023-11-07 US disclosed
US-11561440-B2 Photoalignment composition for the stabilization of the pre-tilt angle in liquid crystal layers Rolic Technologies AG (CH) 2023-01-24 US disclosed
US-20220145009-A1 COLORING RESIN COMPOSITION, FILM, COLOR FILTER, SOLID-STATE IMAGING ELEMENT, AND IMAGE DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2022-05-12 US disclosed
EP-0260709-A1 Fusible and soluble polyamideimide-polyimide block polymers Chemie Linz Gesellschaft m.b.H. (AT) 1988-03-23 EP disclosed
US-4724257-A Aromatic polythioetheramide-imide MITSUBISHI PETROCHEMICAL CO., LTD. (JP) 1988-02-09 US disclosed
US-4716216-A HIGH SOLVENT RESISTANCE GENERAL ELECTRIC COMPANY (US) 1987-12-29 US disclosed
JP-S62151424-A AROMATIC POLYAMIDE COPOLYMER MITSUBISHI PETROCHEM CO LTD 1987-07-06 JP disclosed
EP-0213573-A2 Crystalline polyimides containing cumulative phenylene sulfide units GENERAL ELECTRIC COMPANY (US) 1987-03-11 EP disclosed
EP-0210036-A2 Aromatic poly(thioetheramide-imides) MITSUBISHI PETROCHEMICAL CO., LTD. (JP) 1987-01-28 EP disclosed
US-4621134-A Aromatic polythioetheramide MITSUBISHI PETROCHEMICAL CO., LTD. (JP) 1986-11-04 US disclosed
EP-0162606-A1 Aromatic polythioetheramides and process for their production MITSUBISHI PETROCHEMICAL CO., LTD. (JP) 1985-11-27 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11806661-B2 Polymer and method for producing the same, gas separation membrane, gas separation module, and gas separation apparatus using the polymer, and m-phenylenediamine compound PRMT9, PRMT1, PNMT CYP3A4 1289/4885MAPK1 1124/4885TSHR 1442/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.