Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.38 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.33 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.33 |
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.32 |
| ▸ | CDK4 | P11802 | 1/20 | 0.32 |
| ▸ | CCND3 | P30281 | 1/20 | 0.32 |
| ▸ | MET | P08581 | 1/20 | 0.31 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.31 |
| ▸ | FGFR2 | P21802 | 2/20 | 0.31 |
| ▸ | FGFR4 | P22455 | 2/20 | 0.31 |
| ▸ | FGFR3 | P22607 | 2/20 | 0.31 |
| ▸ | EGFR | P00533 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2983374 | 0.80 | DYRK1A (0.46) | KDM4EALDH1A1HPGDADRA1AHSD17B10 | |
| SCHEMBL27303515 | 0.78 | HDAC6 (0.40) | KDM4EALDH1A1HPGDADRA1AHSD17B10 | |
| SCHEMBL3144585 | 0.76 | HDAC6 (0.40) | KDM4EALDH1A1HPGDADRA1AHSD17B10 | |
| SCHEMBL5034216 | 0.76 | HDAC6 (0.40) | KDM4EALDH1A1HPGDADRA1AHSD17B10 | |
| SCHEMBL27944268 | 0.76 | HSP90AA1 (0.41) | KDM4EALDH1A1HPGDADRA1AHSD17B10 | |
| SCHEMBL5942179 | 0.76 | HDAC6 (0.43) | KDM4EALDH1A1HPGDADRA1AHSD17B10 | |
| SCHEMBL27641128 | 0.74 | KDM4E (0.41) | KDM4EALDH1A1HPGDADRA1AHSD17B10 | |
| SCHEMBL24453428 | 0.73 | HDAC6 (0.41) | KDM4EALDH1A1HPGDADRA1AHSD17B10 | |
| SCHEMBL3157542 | 0.73 | HSD17B10 (0.52) | KDM4EALDH1A1HPGDADRA1AHSD17B10 | |
| SCHEMBL14010824 | 0.73 | KDM4E (0.55) | KDM4EALDH1A1HPGDADRA1AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104788485-B | The method for preparing antiviral agent | 百时美－施贵宝爱尔兰控股公司 | 2017-10-03 | — | — | CN | disclosed |
| CN-104788485-A | Process for preparing antiviral agent | BRISTOL MYERS SQUIBB CO | 2015-07-22 | — | — | CN | disclosed |
| CN-102675355-B | Process for preparing the antiviral agent [1S-(1alpha,3 alpha,4beta)]-2-amino-1,9-dihydro-9-[4-hydroxy-3-(hydroxymethyl)-2-methylenecyclopentyl]-6H-purin-6-one | BRISTOL MYERS SQUIBB CO | 2015-05-06 | — | — | CN | disclosed |