Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.38 |
| ▸ | MET | P08581 | 1/20 | 0.31 |
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.30 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27303515 | 0.78 | HDAC6 (0.40) | HDAC6KDM4EALDH1A1HPGDADRA1A | |
| SCHEMBL24453428 | 0.77 | HDAC6 (0.41) | HDAC6KDM4EALDH1A1HPGDADRA1A | |
| SCHEMBL2983374 | 0.76 | DYRK1A (0.46) | HDAC6KDM4EALDH1A1HPGDADRA1A | |
| SCHEMBL5034216 | 0.76 | HDAC6 (0.40) | HDAC6KDM4EALDH1A1HPGDADRA1A | |
| SCHEMBL5942179 | 0.76 | HDAC6 (0.43) | HDAC6KDM4EALDH1A1HPGDADRA1A | |
| SCHEMBL27944268 | 0.76 | HSP90AA1 (0.41) | HDAC6KDM4EALDH1A1HPGDADRA1A | |
| SCHEMBL28016406 | 0.76 | KDM4E (0.42) | HDAC6KDM4EALDH1A1HPGDADRA1A | |
| SCHEMBL27641128 | 0.74 | KDM4E (0.41) | HDAC6KDM4EALDH1A1HPGDADRA1A | |
| SCHEMBL28384782 | 0.73 | KDM4E (0.40) | HDAC6KDM4EALDH1A1HPGDADRA1A | |
| SCHEMBL14642669 | 0.72 | CDK1 (0.56) | HDAC6KDM4EALDH1A1HPGDADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1551839-B1 | PROCESS FOR PREPARING 9-¬4-ACETOXY-3-(ACETOXYMETHYL)BUT-1-YL -2-AMINOPURINE | KYUNGDONG PHARM CO LTD (KR) | 2010-02-17 | — | — | EP | disclosed |
| US-7041823-B2 | Process for preparing 9-[4-acetoxy-3-(acetoxymethyl)but-1-yl]-2-aminopurine | KYUNGDONG PHARM. CO., LTD. (KR) | 2006-05-09 | — | — | US | disclosed |
| US-20050222413-A1 | Process for preparing 9-[4-acetoxy-3-(acetoxymethyl)but-1-yl]-2-aminopurine | KYUNGDONG PHARM CO., LTD. (KR) | 2005-10-06 | — | — | US | disclosed |
| EP-1551839-A1 | PROCESS FOR PREPARING 9-[4-ACETOXY-3-(ACETOXYMETHYL)BUT-1-YL]-2-AMINOPURINE | Kyungdong Pharm. Co., Ltd. (KR) | 2005-07-13 | — | — | EP | disclosed |
| WO-2004007497-A1 | PROCESS FOR PREPARING 9-[4-ACETOXY-3-(ACETOXYMETHYL)BUT-1-YL]-2-AMINOPURINE | KYUNGDONG PHARM. CO., LTD. (KR) | 2004-01-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050222413-A1 | Process for preparing 9-[4-acetoxy-3-(acetoxymethyl)but-1-yl]-2-aminopurine | TPMT, TYMP, MTAP | HDAC6 1916/4885KDM4E 370/4885ALDH1A1 314/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.