Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | PPM1B | O75688 | 1/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.34 |
| ▸ | PPP1CC | P36873 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.33 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL34461866 | 0.90 | ALOX15 (0.39) | ALOX15SMN1; SMN2GAAKDM4EMEN1 | |
| SCHEMBL3147640 | 0.83 | SMN1; SMN2 (0.35) | ALOX15SMN1; SMN2GAAKDM4EMEN1 | |
| SCHEMBL15927846 | 0.83 | SMN1; SMN2 (0.35) | ALOX15SMN1; SMN2GAAKDM4EMEN1 | |
| SCHEMBL15927847 | 0.83 | SMN1; SMN2 (0.35) | ALOX15SMN1; SMN2GAAKDM4EMEN1 | |
| SCHEMBL4291628 | 0.83 | SMN1; SMN2 (0.35) | ALOX15SMN1; SMN2GAAKDM4EMEN1 | |
| SCHEMBL1964295 | 0.83 | SMN1; SMN2 (0.35) | ALOX15SMN1; SMN2GAAKDM4EMEN1 | |
| SCHEMBL5814077 | 0.80 | SMYD3 (0.35) | ALOX15SMN1; SMN2GAAPOLBPPM1B | |
| SCHEMBL32676486 | 0.80 | SMN1; SMN2 (0.34) | ALOX15SMN1; SMN2GAAKDM4EMEN1 | |
| SCHEMBL4293565 | 0.80 | SMYD3 (0.35) | ALOX15SMN1; SMN2GAAPOLBPPM1B | |
| SCHEMBL30829113 | 0.80 | SMYD3 (0.35) | ALOX15SMN1; SMN2GAAPOLBPPM1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104610415-A | Liver-targeting platinum anticancer drug and synthetic method thereof | KUNMING INST PRECIOUS METALS | 2015-05-13 | — | — | CN | disclosed |