SCHEMBL28017200

SCHEMBL28017200

Cc1cccc(NC(=O)C(N)=O)c1C

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.58
HSD17B10 Q99714 3/20 0.58
ALDH1A1 P00352 3/20 0.58
NPC1 O15118 5/20 0.55
RAB9A P51151 5/20 0.55
LMNA P02545 1/20 0.53
TP53 P04637 1/20 0.53
TSHR P16473 1/20 0.53
HTT P42858 1/20 0.53
PPARG P37231 1/20 0.52
ATM Q13315 1/20 0.51
HDAC3 O15379 1/20 0.51
HDAC4 P56524 1/20 0.51
HDAC1 Q13547 1/20 0.51
HDAC7 Q8WUI4 1/20 0.51
HDAC2 Q92769 1/20 0.51
HDAC10 Q969S8 1/20 0.51
HDAC11 Q96DB2 1/20 0.51
HDAC8 Q9BY41 1/20 0.51
HDAC6 Q9UBN7 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21568076 0.88 NPC1 (0.69) MAPTHSD17B10ALDH1A1NPC1RAB9A
SCHEMBL29892467 0.85 MAPT (0.61) MAPTHSD17B10ALDH1A1NPC1RAB9A
SCHEMBL25356036 0.85 NPC1 (0.77) MAPTHSD17B10ALDH1A1NPC1RAB9A
SCHEMBL1140606 0.85 MAPT (0.61) MAPTHSD17B10ALDH1A1NPC1RAB9A
SCHEMBL881578 0.84 NPC1 (0.58) MAPTHSD17B10ALDH1A1NPC1RAB9A
SCHEMBL21551690 0.83 GPR35 (0.58) MAPTHSD17B10ALDH1A1NPC1RAB9A
Formaldehyde SCHEMBL27427139 0.81 MAPT (0.58) MAPTHSD17B10ALDH1A1NPC1RAB9A
SCHEMBL8765947 0.81 PPARG (0.56) MAPTHSD17B10ALDH1A1NPC1RAB9A
SCHEMBL3380172 0.80 POLB (0.60) MAPTHSD17B10ALDH1A1NPC1RAB9A
SCHEMBL29581522 0.80 GAA (0.70) MAPTHSD17B10ALDH1A1NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105523832-A Special slow release water-soluble fertilizer for soybeans, and preparation method thereof CHENGDU NEW KELI CHEM SCI CO 2016-04-27 CN claimed
CN-104609944-A Special slow release water soluble fertilizer for rubber tree and preparation method thereof CHENGDU NEW KELI CHEM SCI CO 2015-05-13 CN claimed
CN-113453550-A Safe compositions comprising a pyridine carboxylate herbicide and quinoxyacetic acid 科迪华农业科技有限责任公司 2021-09-28 CN disclosed
CN-113271778-A Compositions comprising a carboxypyridine herbicide and a protoporphyrinogen oxidase (PROTOX) inhibitor herbicide 科迪华农业科技有限责任公司 2021-08-17 CN disclosed
CN-113226033-A Compositions comprising chlorofluoropyridinates safe for white clover and methods of use thereof 科迪华农业科技有限责任公司 2021-08-06 CN disclosed
CN-113226036-A Compositions comprising a pyridine carboxylate herbicide and a microtubule assembly inhibitor herbicide 科迪华农业科技有限责任公司 2021-08-06 CN disclosed
CN-112996393-A Compositions comprising a pyridine carboxylate herbicide and a synthetic auxin herbicide or an auxin transport inhibitor 科迪华农业科技有限责任公司 2021-06-18 CN disclosed
CN-112969370-A Compositions comprising a carboxypyridine herbicide and a PDS inhibitor herbicide 科迪华农业科技有限责任公司 2021-06-15 CN disclosed
CN-109414018-B Bactericidal composition for agriculture and horticulture and method for preventing and treating plant diseases 日本史迪士生物科学株式会社 2021-04-20 CN disclosed
CN-105523832-A Special slow release water-soluble fertilizer for soybeans, and preparation method thereof CHENGDU NEW KELI CHEM SCI CO 2016-04-27 CN disclosed
CN-104610088-A A method for synthesizing N, N-dialkyl oxalamide by using CO2 UNIV GUANGDONG TECHNOLOGY 2015-05-13 CN disclosed
CN-104609944-A Special slow release water soluble fertilizer for rubber tree and preparation method thereof CHENGDU NEW KELI CHEM SCI CO 2015-05-13 CN disclosed