Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK1 | Q13464 | 18/20 | 1.00 |
| ▸ | RPS6KA1 | Q15418 | 9/20 | 1.00 |
| ▸ | RPS6KB1 | P23443 | 8/20 | 1.00 |
| ▸ | ROCK2 | O75116 | 1/20 | 1.00 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.45 |
| ▸ | GRK2 | P25098 | 4/20 | 0.45 |
| ▸ | GRK5 | P34947 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29366060 | 1.00 | ROCK1 (1.00) | ROCK1RPS6KA1RPS6KB1ROCK2GPBAR1 | |
| SCHEMBL3883866 | 0.90 | ROCK1 (0.81) | ROCK1RPS6KA1RPS6KB1ROCK2GRK2 | |
| SCHEMBL3884436 | 0.90 | ROCK1 (0.81) | ROCK1RPS6KA1RPS6KB1ROCK2GRK2 | |
| SCHEMBL3886366 | 0.90 | ROCK1 (0.81) | ROCK1RPS6KA1RPS6KB1ROCK2GRK2 | |
| SCHEMBL3884422 | 0.90 | ROCK1 (0.81) | ROCK1RPS6KA1RPS6KB1ROCK2GPBAR1 | |
| SCHEMBL3884121 | 0.90 | ROCK1 (0.81) | ROCK1RPS6KA1RPS6KB1ROCK2GRK2 | |
| SCHEMBL3888074 | 0.88 | ROCK1 (0.79) | ROCK1RPS6KA1RPS6KB1ROCK2GRK2 | |
| SCHEMBL3897868 | 0.88 | ROCK1 (0.78) | ROCK1RPS6KA1RPS6KB1ROCK2GRK2 | |
| SCHEMBL3864374 | 0.87 | ROCK1 (0.77) | ROCK1RPS6KA1RPS6KB1ROCK2GRK2 | |
| SCHEMBL3883513 | 0.86 | ROCK1 (1.00) | ROCK1RPS6KA1RPS6KB1ROCK2GRK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 252 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4692329-A1 | COMPOSITION FOR INDUCING DIRECT DIFFERENTIATION OF STEM CELLS INTO CORNEAL ENDOTHELIAL CELLS AND METHOD FOR INDUCING DIRECT DIFFERENTIATION USING SAME | The Asan Foundation (KR) | 2026-02-11 | — | — | EP | claimed |
| EP-4636079-A1 | METHOD FOR INDUCING DIFFERENTIATION OF STEM CELLS INTO CORNEAL ENDOTHELIAL CELLS AND USE THEREOF | The Asan Foundation (KR) | 2025-10-22 | — | — | EP | claimed |
| US-12371664-B2 | Medium for direct differentiation of pluripotent stem cell-derived mesenchymal stem cell, method for preparing mesenchymal stem cell by using same, and mesenchymal stem cell prepared thereby | CHA BIOTECH CO., LTD. (KR) | 2025-07-29 | — | — | US | claimed |
| WO-2024210619-A1 | COMPOSITION FOR INDUCING DIRECT DIFFERENTIATION OF STEM CELLS INTO CORNEAL ENDOTHELIAL CELLS AND METHOD FOR INDUCING DIRECT DIFFERENTIATION USING SAME | 재단법인 아산사회복지재단 | 2024-10-10 | — | — | WO | claimed |
| US-20210340498-A1 | MEDIUM FOR DIRECT DIFFERENTIATION OF PLURIPOTENT STEM CELL-DERIVED MESENCHYMAL STEM CELL, METHOD FOR PREPARING MESENCHYMAL STEM CELL BY USING SAME, AND MESENCHYMAL STEM CELL PREPARED THEREBY | CHA BIOTECH CO., LTD. (KR) | 2021-11-04 | — | — | US | claimed |
| EP-3848455-A1 | MEDIUM FOR DIRECT DIFFERENTIATION OF PLURIPOTENT STEM CELL-DERIVED MESENCHYMAL STEM CELL, METHOD FOR PREPARING MESENCHYMAL STEM CELL BY USING SAME, AND MESENCHYMAL STEM CELL PREPARED THEREBY | CHA Biotech Co., Ltd. (KR) | 2021-07-14 | — | — | EP | claimed |
| CN-112996903-A | Culture medium for directly differentiating pluripotent stem cell-derived mesenchymal stem cells, method for preparing mesenchymal stem cells by using culture medium and mesenchymal stem cells prepared by using culture medium | 车比奥泰有限公司 | 2021-06-18 | — | — | CN | claimed |
| US-20200140827-A1 | A SUBSTRATE AND METHOD FOR THE GENERATION OF INDUCED PLURIPOTENT STEM CELLS | THE QUEEN'S UNIVERSITY OF BELFAST (GB) | 2020-05-07 | — | — | US | claimed |
| EP-3630953-A1 | A SUBSTRATE AND METHOD FOR THE GENERATION OF INDUCED PLURIPOTENT STEM CELLS | The Queen's University Of Belfast (GB) | 2020-04-08 | — | — | EP | claimed |
| WO-2018220081-A1 | A SUBSTRATE AND METHOD FOR THE GENERATION OF INDUCED PLURIPOTENT STEM CELLS | THE QUEEN'S UNIVERSITY OF BELFAST (GB) | 2018-12-06 | — | — | WO | claimed |
| US-20160230142-A1 | CORNEAL STROMAL KERATOCYTE CULTURE | SINGAPORE HEALTH SERVICES PTE LTD (SG) | 2016-08-11 | — | — | US | claimed |
| EP-3047018-A1 | CORNEAL STROMAL KERATOCYTE CULTURE | Singapore Health Services Pte Ltd (SG) | 2016-07-27 | — | — | EP | claimed |
| WO-2015041606-A1 | CORNEAL STROMAL KERATOCYTE CULTURE | SINGAPORE HEALTH SERVICES PTE LTD (SG) | 2015-03-26 | — | — | WO | claimed |
| US-7592357-B2 | Compounds | SMITHKLINE BEECHAM CORPORATION (US) | 2009-09-22 | — | — | US | claimed |
| EP-1718638-A4 | NOVEL COMPOUNDS | SMITHKLINE BEECHAM CORP (US) | 2009-04-22 | — | — | EP | claimed |
| US-20080058384-A1 | Novel Compounds | GLAXOSMITHKLINE LLC | 2008-03-06 | — | — | US | claimed |
| EP-1718638-A1 | NOVEL COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 2006-11-08 | — | — | EP | claimed |
| WO-2005082890-A1 | NOVEL COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 2005-09-09 | — | — | WO | claimed |
| US-20260124250-A1 | METHODS FOR SELECTING CULTURED CORNEAL ENDOTHELIAL CELLS | UNIV MAASTRICHT (NL) | 2026-05-07 | — | — | US | disclosed |
| WO-2005082890-A1 | NOVEL COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 2005-09-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260124250-A1 | METHODS FOR SELECTING CULTURED CORNEAL ENDOTHELIAL CELLS | TAGLN2, CNN2, TMIGD3 | ROCK1 810/4885RPS6KA1 3410/4885RPS6KB1 2954/4885 |
| US-20080058384-A1 | Novel Compounds | ARHGDIB, TNK2, ROCK2 | ROCK1 6/4885RPS6KA1 304/4885RPS6KB1 195/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.