Urea

Urea

SCHEMBL28017752

CCC[Si](OCC)(OCC)OCC.CO.NC(N)=O

nearest known ligand 0.37

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Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 1/20 0.37
LMNA P02545 1/20 0.32
HSD17B10 Q99714 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Urea SCHEMBL1483244 0.98 ALOX15 (0.39) ALOX15LMNAHSD17B10
Urea SCHEMBL5532577 0.98 ALOX15 (0.39) ALOX15LMNAHSD17B10
Carbamic Acid SCHEMBL29039766 0.91 ALOX15 (0.37) ALOX15LMNAHSD17B10
Butyramide SCHEMBL29188985 0.85 SOAT1 (0.33) ALOX15
Hydrazinecarboxamide SCHEMBL28980554 0.85 CYP1A2 (0.40) ALOX15LMNA
Acrylamide SCHEMBL2854180 0.84 TSHR (0.42) ALOX15
SCHEMBL5088965 0.84 TDP1 (0.46) ALOX15
Methylamine SCHEMBL358320 0.83
SCHEMBL24959 0.83
Butyramide SCHEMBL29188994 0.82 MEN1 (0.32) ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104628760-A Synthesis preparation method of urea propyl triethoxysilane-methanol solution JINGZHOU JIANGHAN FINE CHEMICAL CO LTD 2015-05-20 CN disclosed
CN-104628760-A Synthesis preparation method of urea propyl triethoxysilane-methanol solution JINGZHOU JIANGHAN FINE CHEMICAL CO LTD 2015-05-20 CN disclosed