Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 4/20 | 0.53 |
| ▸ | EGFR | P00533 | 1/20 | 0.44 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28017878 | 0.85 | TRPA1 (0.75) | TRPA1KMT2AHPGDMEN1ALDH1A1 | |
| SCHEMBL16894195 | 0.85 | TRPA1 (0.72) | TRPA1EGFRERBB2KMT2AMEN1 | |
| SCHEMBL28017925 | 0.83 | TRPA1 (0.76) | TRPA1KMT2AMEN1ALDH1A1 | |
| SCHEMBL28017376 | 0.73 | DAGLA (0.43) | HPGDALDH1A1 | |
| SCHEMBL16894198 | 0.69 | TRPA1 (1.00) | TRPA1L3MBTL1ALDH1A1 | |
| SCHEMBL16894096 | 0.68 | TRPA1 (1.00) | TRPA1L3MBTL1ALDH1A1 | |
| SCHEMBL16894237 | 0.67 | TRPA1 (0.68) | TRPA1 | |
| SCHEMBL16894107 | 0.67 | TRPA1 (0.69) | TRPA1KMT2ALMNAMEN1POLB | |
| SCHEMBL30259901 | 0.67 | NPC1 (0.59) | TP53LMNAHPGDNPC1 | |
| SCHEMBL11920201 | 0.67 | SRC (0.65) | EGFRERBB2TP53NPC1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104684899-A | Substituted sulfonamide compounds | HOFFMANN LA ROCHE | 2015-06-03 | — | — | CN | disclosed |