Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM4 | Q14833 | 8/20 | 0.51 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.45 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | DHFR | P00374 | 3/20 | 0.42 |
| ▸ | LCK | P06239 | 1/20 | 0.41 |
| ▸ | KDR | P35968 | 1/20 | 0.41 |
| ▸ | JAK3 | P52333 | 1/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29509257 | 0.81 | LCK (0.50) | KDM4EDHFRLCKKDRJAK3 | |
| SCHEMBL41506 | 0.81 | LCK (0.50) | KDM4EDHFRLCKKDRJAK3 | |
| Hydrochloric Acid SCHEMBL28230152 | 0.79 | LCK (0.49) | KDM4EPKMRAB9ADHFRLCK | |
| Hydrochloric Acid SCHEMBL29486326 | 0.79 | LCK (0.49) | KDM4EPKMRAB9ADHFRLCK | |
| Hydrochloric Acid SCHEMBL3468306 | 0.79 | LCK (0.49) | KDM4EPKMRAB9ADHFRLCK | |
| Hydrochloric Acid SCHEMBL17237902 | 0.77 | LCK (0.47) | KDM4ELMNAPKMRAB9ADHFR | |
| Naphthalene SCHEMBL8156208 | 0.73 | RELA (0.54) | GRM4HDAC6KDM4ENPC1LMNA | |
| Biphenyl SCHEMBL28889831 | 0.72 | ADORA2A (0.51) | PDGFRBPDGFRANPC1RAB9ADHFR | |
| SCHEMBL29784099 | 0.71 | PDGFRB (0.56) | PDGFRBPDGFRAKDM4ENPC1LMNA | |
| SCHEMBL4498563 | 0.71 | PDGFRB (0.56) | PDGFRBPDGFRAKDM4ENPC1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105017162-B | 4 pairs of propenylbenzene amido quinazoline derivatives and its application in antineoplastic is prepared | 陕西师范大学 | 2017-10-27 | — | — | CN | disclosed |
| CN-105017162-A | 4-P-propenylphenylaminoquinazoline derivative and application thereof in preparation of antitumor drugs | UNIV SHAANXI NORMAL | 2015-11-04 | — | — | CN | disclosed |