Known targets — ChEMBL curated mechanism
MMP1MMP13MMP7MMP8polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Isopropyl Alcohol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 6/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Isopropyl Alcohol SCHEMBL2390379 | 0.96 | TSHR (0.46) | TSHRALDH1A1LMNATDP1SMN1; SMN2 | |
| Isopropyl Alcohol SCHEMBL10935224 | 0.93 | ALDH1A1 (0.50) | TSHRALDH1A1LMNATDP1SMN1; SMN2 | |
| Isopropyl Alcohol SCHEMBL467976 | 0.93 | — | — | |
| Isopropyl Alcohol SCHEMBL28090499 | 0.90 | ALDH1A1 (0.40) | TSHRALDH1A1LMNATDP1SMN1; SMN2 | |
| Isopropyl Alcohol SCHEMBL23045053 | 0.89 | — | — | |
| Isopropyl Alcohol SCHEMBL6048230 | 0.89 | — | — | |
| Isopropyl Alcohol SCHEMBL28187813 | 0.89 | — | — | |
| Isopropyl Alcohol SCHEMBL9566330 | 0.89 | — | — | |
| Isopropyl Alcohol SCHEMBL28841770 | 0.89 | — | — | |
| Isopropyl Alcohol SCHEMBL28326654 | 0.89 | ALDH1A1 (0.46) | TSHRALDH1A1LMNATDP1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021155050-A1 | KINASE MODULATORS, PHARMACEUTICAL COMPOSITIONS, AND THERAPEUTIC APPLICATIONS | BIOTHERYX, INC. (US) | 2021-08-05 | — | — | WO | disclosed |
| WO-2017162475-A9 | METHOD OF FORMING A MULTILAYER COATING FILM | BASF COATINGS GMBH (DE) | 2019-10-17 | — | — | WO | disclosed |
| CN-103502315-B | Composition and polymer | 旭化成株式会社 | 2016-08-17 | — | — | CN | disclosed |
| CN-105802209-A | Solution of aromatic polyamide for producing display element, optical element, illumination element or sensor element | 亚克朗聚合物系统公司 | 2016-07-27 | — | — | CN | disclosed |
| CN-103688340-B | Diffusing agent composition, method for forming impurity diffusion layer, and solar cell | 东京应化工业株式会社 | 2016-07-20 | — | — | CN | disclosed |
| CN-105754099-A | Composition and polymer | 旭化成株式会社 | 2016-07-13 | — | — | CN | disclosed |
| US-7780989-B2 | Process for the preparation of crystalline nano-particle dispersions | ASTRAZENECA AB (SE) | 2010-08-24 | — | — | US | disclosed |
| US-20050202092-A1 | Process for the preparation of crystalline nano-particle dispersions | ASTRAZENECA AB (SE) | 2005-09-15 | — | — | US | disclosed |