Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | YTHDC1 | Q96MU7 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.39 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | SLC18A3 | Q16572 | 2/20 | 0.38 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | G6PC1 | P35575 | 1/20 | 0.36 |
| ▸ | GBA1 | P04062 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28018410 | 1.00 | YTHDC1 (0.43) | YTHDC1SLC6A2SLC6A4SLC6A3DPP8 | |
| SCHEMBL26038459 | 1.00 | YTHDC1 (0.43) | YTHDC1SLC6A2SLC6A4SLC6A3DPP8 | |
| SCHEMBL26038458 | 1.00 | YTHDC1 (0.43) | YTHDC1SLC6A2SLC6A4SLC6A3DPP8 | |
| SCHEMBL1543202 | 0.92 | SLC6A2 (0.42) | YTHDC1SLC6A2SLC6A4SLC6A3DPP8 | |
| SCHEMBL1543203 | 0.92 | SLC6A2 (0.42) | YTHDC1SLC6A2SLC6A4SLC6A3DPP8 | |
| SCHEMBL1543200 | 0.92 | SLC6A2 (0.42) | YTHDC1SLC6A2SLC6A4SLC6A3DPP8 | |
| SCHEMBL384299 | 0.90 | SLC6A2 (0.49) | YTHDC1SLC6A2SLC6A4SLC6A3DPP8 | |
| SCHEMBL481896 | 0.90 | SLC6A2 (0.49) | YTHDC1SLC6A2SLC6A4SLC6A3DPP8 | |
| SCHEMBL384300 | 0.90 | SLC6A2 (0.49) | YTHDC1SLC6A2SLC6A4SLC6A3DPP8 | |
| SCHEMBL15689071 | 0.88 | SLC6A2 (0.43) | YTHDC1SLC6A2SLC6A4SLC6A3DPP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104592231-A | Novel Tricyclic Compounds | ABBVIE INC | 2015-05-06 | — | — | CN | disclosed |