Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | DPP4 | P27487 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CTSS | P25774 | 1/20 | 0.30 |
| ▸ | CTSK | P43235 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28224248 | 0.81 | DPP4 (0.35) | DPP4 | |
| SCHEMBL9709360 | 0.79 | HCAR2 (0.36) | DPP4 | |
| SCHEMBL1107368 | 0.76 | GAA (0.44) | GAATSHRALDH1A1 | |
| SCHEMBL28287215 | 0.72 | GAA (0.41) | GAATSHRALDH1A1 | |
| Acetonitrile SCHEMBL28018562 | 0.72 | GAA (0.41) | GAATSHRALDH1A1CTSSCTSK | |
| SCHEMBL10186576 | 0.71 | HPGD (0.44) | DPP4ALDH1A1CTSK | |
| SCHEMBL9719394 | 0.71 | — | — | |
| Water SCHEMBL27601078 | 0.70 | — | — | |
| SCHEMBL28725859 | 0.70 | GAA (0.39) | GAATSHRALDH1A1 | |
| SCHEMBL28787477 | 0.70 | GAA (0.39) | GAATSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104703991-B | Macrocyclic Inhibitors of Flaviviridae Viruses | 吉利德科学公司 | 2018-03-23 | — | — | CN | disclosed |
| CN-104703991-A | Macrocyclic inhibitors of flaviviridae viruses | GILEAD SCIENCES INC | 2015-06-10 | — | — | CN | disclosed |