Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.31 |
| ▸ | GABRP | O00591 | 2/20 | 0.31 |
| ▸ | GABRD | O14764 | 2/20 | 0.31 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.31 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.31 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.31 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.31 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.31 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.31 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.31 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.31 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.31 |
| ▸ | GABRE | P78334 | 2/20 | 0.31 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.31 |
| ▸ | GABRG1 | Q8N1C3 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1107368 | 0.81 | GAA (0.44) | GAATSHRCYP2C19CYP2D6CYP2C9 | |
| SCHEMBL676410 | 0.78 | TSHR (0.41) | TSHRALDH1A1 | |
| Hydrochloric Acid SCHEMBL9794913 | 0.78 | TSHR (0.37) | TSHR | |
| Isopropylamine SCHEMBL28156605 | 0.77 | GAA (0.41) | GAATSHRCYP2C19CYP2D6ALDH1A1 | |
| SCHEMBL28287215 | 0.77 | GAA (0.41) | GAATSHRCYP2C19CYP2D6CYP2C9 | |
| Acetic Acid Methyl Ester SCHEMBL28141851 | 0.76 | ALDH1A1 (0.46) | TSHRALDH1A1 | |
| Hydrochloric Acid SCHEMBL5722210 | 0.76 | TSHR (0.39) | TSHRALDH1A1 | |
| SCHEMBL8605101 | 0.75 | GAA (0.39) | GAATSHRCYP2C19CYP2D6CYP2C9 | |
| SCHEMBL16087960 | 0.75 | GAA (0.39) | GAATSHRCYP2C19CYP2D6CYP2C9 | |
| SCHEMBL14178083 | 0.75 | KCNH2 (0.31) | CYP2C19CYP2D6CYP2C9ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105007909-B | Use of formyl peptide receptor 2 agonists for the treatment of ocular inflammatory diseases | 阿勒根公司 | 2019-06-28 | — | — | CN | claimed |
| CN-105705484-B | Carbanilate derivative as formyl peptide receptor conditioning agent | 阿勒根公司 | 2018-09-14 | — | — | CN | claimed |
| CN-105007908-B | Use of agonists of formyl peptide receptor 2 for the treatment of skin diseases | 阿勒根公司 | 2017-10-03 | — | — | CN | claimed |
| CN-105705484-A | Phenylcarbamate derivatives as formyl peptide receptor modulators | 阿勒根公司 | 2016-06-22 | — | — | CN | claimed |
| CN-105007909-A | Use of formyl peptide receptor 2 agonists for the treatment of ocular inflammatory diseases | ALLERGAN INC | 2015-10-28 | — | — | CN | claimed |
| CN-105007908-A | Use of agonists of formyl peptide receptor 2 for the treatment of skin diseases | ALLERGAN INC | 2015-10-28 | — | — | CN | claimed |
| CN-104945309-B | New nitroso compound and application thereof as nitroxyl donors | 卡尔迪奥克斯尔制药公司 | 2019-06-04 | — | — | CN | disclosed |
| CN-105705484-A | Phenylcarbamate derivatives as formyl peptide receptor modulators | 阿勒根公司 | 2016-06-22 | — | — | CN | disclosed |
| CN-102076342-A | Novel nitroso compounds as nitroxyl donors and methods of use thereof | CARDIOXYL PHARMACEUTICALS INC | 2011-05-25 | — | — | CN | disclosed |